Monthly Archives: July 2023

Fighting brain cancer

“Don’t eat me!” That’s how one might translate the signal that the cancer cells in a glioblastoma send to the macrophages (white blood cells specialized in removing dead and dying cellular matter) in the brain. Immunotherapy attempts to enable these cells to eradicate the abnormal cells, but so far, it has met with little success […]

Researchers reveal how NSAIDs worsen C. difficile infections

A medical illustration of Clostridioides difficile bacteria, formerly known as Clostridium difficile, presented in the Centers for Disease Control and Prevention (CDC) publication entitled, Antibiotic Resistance Threats in the United States, 2019. Credit: CDC Why do nonsteroidal anti-inflammatory drugs (NSAIDs) exacerbate gastrointestinal infections by Clostridioides difficile, the leading cause of antibiotic-associated diarrhea worldwide? In a […]

Lenvatinib/Pembrolizumab Elicits High, Durable Responses in Advanced RCC

Lenvatinib (Lenvima) with pembrolizumab (Keytruda) elicited higher, more durable responses and improved survival outcomes compared with sunitinib (Sutent) in the treatment of patients with advanced renal cell carcinoma (RCC), according to findings from the phase 3 CLEAR study (NCT02811861). In data presented at the 2023 Kidney Cancer Research Summit, the objective response rate (ORR) was […]

Weekend Warrior Activity Patterns Associated with Low Risk of Cardiovascular Outcomes

Patrick T. Ellinor, MD, PhD Credit: Massachusetts General Hospital A “weekend warrior” physical activity pattern, meaning most moderate to vigorous activity was achieved over 1 to 2 days, was associated with a similarly lower risk of cardiovascular outcomes as evenly distributed activity, according to new research.1 The analysis of nearly 90,000 individuals providing a week […]

CHOP Researchers Reveal How NSAIDs Worsen C. difficile Infections

–Study shows that NSAIDs disrupt epithelial cells in the colon and sensitize them to C. difficile toxins by perturbing cell mitochondria— PHILADELPHIA, July 19, 2023 /PRNewswire/ — Why do nonsteroidal anti-inflammatory drugs (NSAIDs) exacerbate gastrointestinal infections by Clostridioides difficile, the leading cause of antibiotic-associated diarrhea worldwide? In a new paper published in Science Advances, researchers at […]

Common genetic variation responsible for mediating SARS-CoV-2 asymptomatic infection

Have you ever wondered why some people never became sick from COVID-19? A study published today in Nature shows that common genetic variation among people is responsible for mediating SARS-CoV-2 asymptomatic infection. The results indicate that individuals having this variant never feel sick once infected. This exciting discovery was a result of a U.S.-Australia collaborative […]

A women went to Mexico for an experimental multiple sclerosis treatment. She developed a life-threatening meningitis infection from contaminated equipment.

A patient traveled to Mexico to get an experimental stem cell therapy for multiple sclerosis. She returned with bacterial meningitis, a potentially fatal disease, from contaminated medical equipment. Her doctor told Insider that patients shouldn’t go abroad for medical procedures: “The risk isn’t worth it.”  Loading Something is loading. Thanks for signing up! Access your […]

Hoxworth Blood Center Urgently Seeking Donors

<a href="https://media2.citybeat.com/citybeat/imager/u/original/15642084/news_ohio_buckeyeflame_blooddonation_pexels-charliehelen-rob.png" rel="contentImg_gal-15642076" title="Photo: Charlie Helen-Robinson, Pexels" data-caption="   Photo: Charlie Helen-Robinson, Pexels ” class=”uk-display-block uk-position-relative uk-visible-toggle”> click to enlarge Hoxworth Blood Center, the second oldest blood bank in the country and internationally-recognized leading center in transfusion medicine, is urgently seeking blood donors. Hoxworth Blood serves over 30 hospitals and medical centers in the area and […]

Saving surgical patients’ blood, cleaning it, and giving it back

BANGOR — For nearly 20 years, Northern Light Eastern Maine Medical Center has been leading the way in decreasing blood loss and providing an alternative to receiving transfused blood during surgery. The perioperative autologous blood collection and processing program, or Cell-Saver Program, was launched at the medical center by a few cardiac nurses during coronary […]

Joliet bank sponsors Route 66 blood drive at Rialto Theater

As a founder of the Red Cross Illinois River Valley Chapter in Romeoville, Jim Rolfe knew the importance of blood drives. But Rolfe, senior vice president and corporate relations officer at Old National Bank, felt the value of those drives April 10 when a mass shooting occurred in Louisville, Kentucky. “That happened at one of […]