Abstract Recent studies have documented frequent evolution of clones carrying common cancer mutations in apparently normal tissues, which are implicated in cancer development1,2,3. However, our knowledge is still missing with regard to what additional driver events take place in what order, before one or more of these clones in normal tissues ultimately evolve to cancer. […]
The Cornell University Hospital for Animals has added a cutting-edge service for companion animals: a new technology capable of cleansing patients’ blood outside of their bodies. This opens the door to several new treatment options, including dialysis for animals with kidney failure and immune-mediated diseases. The new technology – an extracorporeal blood purification (EBP) unit […]
Döffinger R, Helbert MR, Barcenas-Morales G, Yang K, Dupuis S, Ceron-Gutierrez L, Espitia-Pinzon C, Barnes N, Bothamley G, Casanova JL, Longhurst HJ, Kumararatne DS. Autoantibodies to interferon-gamma in a patient with selective susceptibility to mycobacterial infection and organ-specific autoimmunity. Clin Infect Dis. 2004;38(1):e10–4. Article PubMed Google Scholar Browne SK, Burbelo PD, Chetchotisakd P, Suputtamongkol Y, […]
Abstract Currently, treatment allocation of patients with Mantle Cell Lymphoma (MCL) is mainly based on age and medical fitness. The combined MCL International Prognostic Index (MIPI-c) allows to predict prognosis using clinical factors (MIPI) and the Ki-67 index. However, high p53 expression as surrogate for TP53 alterations has demonstrated to be an independent predictor for […]
Abstract Aim To conduct a systematic review and meta-analysis assessing whether vision and/or eye disorders are associated with Autism Spectrum Disorder (ASD). Method Based on a pre-registered protocol (PROSPERO: CRD42022328485), we searched PubMed, Web of Knowledge/Science, Ovid Medline, Embase and APA PsycINFO up to 5th February 2022, with no language/type of document restrictions. We included […]
SARANAC LAKE — Following a season of declining donations, the American Red Cross has put out a call for help as it seeks to avert a shortage of blood. When a donor makes and keeps an appointment to give blood or platelets in the weeks ahead, they can help ensure trauma patients, those undergoing cancer […]
Key Points Question What percentage of birthing adults in the US with prepregnancy cardiovascular disease risk factors or adverse pregnancy outcomes received cardiovascular health counseling at the postpartum visit from 2016 through 2020? Findings In a serial cross-sectional analysis of nationally representative data from the Pregnancy Risk Assessment Monitoring System, prevalence of self-reported postpartum counseling […]
A series of blood drives sponsored by Berrien County first responders is planned for the coming week. Cathy Ramirez with Versiti Blood Center of Michigan tells us the Battle Royale for blood donations will enable anyone to show their support for police, fire, and EMT personnel while helping the community. Versiti approached local agencies about […]
For many new moms in recent years, the 4- to 6-week postpartum check-up still lacked cardiovascular health (CVH) counseling, according to nationally representative survey data. About 50% to 60% of these women reported receiving counseling on healthy eating, exercise, and postpartum weight loss after giving birth in the U.S. from 2016 through 2020, reported Sadiya […]
The company said the safety data seen in this study is consistent with the known magrolimab profile and adverse events that are typical in this patient population. However, it recommends discontinuing treatment with magrolimab in patients with MDS. Magrolimab is a monoclonal antibody with potentially first-in-class potential. It binds to CD47, a surface protein commonly […]