CAMBRIDGE, Mass.–(BUSINESS WIRE)– Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today announced it has entered into a strategic agreement with Roche to develop and commercialize zilebesiran, Alnylam’s investigational RNAi therapeutic for the treatment of hypertension, which is currently in Phase 2 of development. The partnership allows for a bold development plan with […]
Monthly Archives: July 2023
Cardiovascular
Lee Health’s Dr. Paul DiGiorgi selected as president of the Florida Society of Thoracic and Cardiovascular Surgeons
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Dr. Paul DiGiorgi Dr. Paul DiGiorgi Lee Health’s Dr. Paul DiGiorgi has been named the incoming president of the Florida Society of Thoracic and Cardiovascular Surgeons. Dr. DiGiorgi was previously secretary/treasurer. He will replace immediate past president Dr. Gregory J. England from Panama City Beach. As president, Dr. DiGiorgi will focus on continuing the Society’s […]
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Pictured: Pfizer’s sign at its La Jolla campus/iStock, JHVEPhoto As the infectious diseases market expands, Pfizer, Gilead and GSK will climb to the top of the industry and emerge as the most dominant players in the space, according to data analytics and consultancy GlobalData. In an industry analysis posted Wednesday, GlobalData projected that the infectious […]
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HONOLULU — Kaiser Permanente Moanalua Medical Center has received American Heart Association Get With The Guidelines® and Mission: Lifeline® achievement awards for demonstrating a commitment to following up-to-date, research-based guidelines for the treatment of heart disease and stroke, ultimately leading to more lives saved, shorter recovery times, and fewer readmissions to the hospital. Every 40 […]
Infection
Incidence of nontuberculous mycobacteria infections among persons with cystic fibrosis in the United States (2010–2019)
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Dean SG, Ricotta EE, Fintzi J, Lai YL, Kadri SS, Olivier KN, et al. Mycobacterial testing Trends, United States, 2009–2015(1). Emerg Infect Dis. 2020;26(9):2243–6. Article PubMed PubMed Central Google Scholar Winthrop KL, Marras TK, Adjemian J, Zhang H, Wang P, Zhang Q. Incidence and prevalence of Nontuberculous Mycobacterial Lung Disease in a large U.S. Managed […]
Cancer and neoplasms
Comparative Effectiveness of Anticoagulants in Patients With Cancer-Associated Thrombosis
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Key Points Question What are the patterns of anticoagulant utilization and the anticoagulants associated with the lowest risk for venous thromboembolism (VTE) recurrence in patients with cancer in a clinical setting? Findings In this comparative effectiveness study with 5100 adult patients, twice as many patients were prescribed direct oral anticoagulants (DOACs) as other classes, and […]
Cardiovascular
Adults with HIV can lower risk for cardiovascular disease with daily statin, study finds
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July 24, 2023 2 min read Source/Disclosures Published by: Source: Grinspoon S, et al. Key REPRIEVE results and the utility of statins among people living with HIV: What have we learned? Presented at: International AIDS Society Conference on HIV Science; July 23-26, 2023; Brisbane, Australia. Disclosures: Grinspoon reports receiving consulting fees from Marathon Asset Management, […]
Congenital disorders
A prospective cohort study protocol: monitoring and surveillance of adverse events following heterologous booster doses of Oxford AstraZeneca COVID-19 vaccine in previous recipients of two doses of Sinopharm or Sputnik V vaccines in Iran
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Objectives General objective Measuring safety of the booster doses of AstraZeneca vaccine in people vaccinated with two doses of Sinopharm or Sputnik V vaccines in Iran. Specific objectives 1) To Estimate the incidence of different types of serious adverse events (SAEs) within 13 weeks in all enrolled vaccinated individuals after either the first or second […]
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Newswise — LOS ANGELES (July 24, 2023) — Cedars-Sinai Guerin Children’s investigators have advanced our understanding of the role that blood platelets play in Kawasaki disease, a serious illness that primarily affects children younger than 5 years old and causes their blood vessels to swell. The findings, published in the peer-reviewed journal JCI Insight, may guide the […]
Cancer and neoplasms
A network medicine approach to study comorbidities in heart failure with preserved ejection fraction
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Oktay AA, Rich JD, Shah SJ. The emerging epidemic of heart failure with preserved ejection fraction. Curr Heart Fail Rep. 2013;10:401–10. Article PubMed Google Scholar Dunlay SM, Roger VL, Redfield MM. Epidemiology of heart failure with preserved ejection fraction. Nat Rev Cardiol. 2017;14:591–602. Article PubMed Google Scholar Mishra S, Kass DA. Cellular and molecular pathobiology […]