Red State Loses Key Cardiologist; Semaglutide Reduces CVD Risk; Pregnancy OK in HCM

The director of the only pediatric heart transplant program in Louisiana, a married gay man, says he is relocating to New York for a better LGBTQ+ environment. (Advocate)

Once-weekly semaglutide 2.4 mg (Wegovy) reduced major adverse cardiovascular events by 20% in the SELECT trial of patients with a body mass index (BMI) ≥27 and established cardiovascular disease, Novo Nordisk said.

Cardiovascular disease was the leading cause of death for every ethnic group across the U.S. from 2000 to 2019. (The Lancet)

Just over three in four Americans with atherosclerotic cardiovascular disease were on secondary prevention statins before the COVID-19 pandemic. (Circulation: Cardiovascular Quality and Outcomes)

High cardiac troponin I levels were linked to all-cause mortality in an unselected population that mostly had no clinical indication for testing. (Heart)

Pregnancy did not hurt long-term cardiac outcomes in women with hypertrophic cardiomyopathy (HCM). (European Journal of Preventive Cardiology)

For septal reduction of hypertrophic obstructive cardiomyopathy, a novel transapical beating-heart septal myectomy appeared successful in several dozen people in a first-in-human study. (Journal of the American College of Cardiology)

People with obstructive sleep apnea taking beta-blockers tended to have more cardiovascular events in subsequent years. (Lancet Regional Health-Europe)

In Colombia, breast cancer patients with higher BMI were more likely to develop cardiotoxicity from chemotherapy, according to a study presented at the American College of Cardiology Latin America meeting.

In survivors of stroke/transient ischemic attack with periodontal disease, intensive treatment for the latter was no better than standard treatment in preventing cardiovascular events in the PREMIERS trial. (Stroke)

The FDA approved a label change for cardiac ablation catheters to indicate a zero-fluoroscopy workflow during atrial fibrillation (Afib) ablation, Biosense Webster announced.

Simultaneous assessment in people with early-stage Afib revealed an imbalance between electrical and mechanical activity in the heart. (Nature Communications)

SGLT2 inhibitors benefitted patients with heart failure with preserved ejection fraction by reducing pulmonary capillary wedge pressure at rest and during exercise. (Circulation)

School-based cardiovascular health education did not result in healthier habits among adolescents in Spain. (JAMA Cardiology)

Clinical decision support tools did not help smaller primary care practices narrow racial gaps in aspirin use, blood pressure control, cholesterol management, and smoking cessation quality metrics. (JAMA Network Open)

A tiny model heart, smaller than a grain of rice, was developed for precision drug testing. (Nature Biomedical Engineering)

Scientists determined how high blood pressure causes arteries in the brain to remain constricted in mice, which may be relevant to work in vascular dementia. (Proceedings of the National Academy of Sciences)

Targeted hypothermia did not result in better functional outcome assessed with a focus on societal participation and cognitive function versus normothermia at 6 months after cardiac arrest, the TTM2 trialists reported. (JAMA Neurology)

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