Congenital disorders
Prognostic models for estimating severity of disease and predicting 30-day mortality of Hypervirulent Klebsiella pneumoniae infections: a bicentric retrospective study
Aug
Russo TA, Marr CM. Hypervirulent Klebsiella pneumoniae. Clin Microbiol Rev. 2019;32(3):e00001-00019.
Google Scholar
Maheswaranathan M, Ngo T, Rockey DC. Identification and management of the Hypervirulent invasive Klebsiella pneumoniae syndrome: a unique and distinct clinical entity. J Invest Med High Impact Case Rep. 2018;6:2324709618806552.
Shon AS, Bajwa RP, Russo TA. Hypervirulent (hypermucoviscous) Klebsiella pneumoniae: a new and dangerous breed. Virulence. 2013;4(2):107–18.
Google Scholar
Lee CR, Lee JH, Park KS, Jeon JH, Kim YB, Cha CJ, et al. Antimicrobial resistance of Hypervirulent Klebsiella pneumoniae: epidemiology, hypervirulence-associated determinants, and resistance mechanisms. Front Cell Infect Microbiol. 2017;7:483.
Google Scholar
Guo MY, Liu Y, Fei B, Ren YY, Liu XW, Zhao ZJ, et al. Research progress on virulence factors of Hypervirulent Klebsiella pneumoniae. Zhonghua Yu Fang Yi Xue Za Zhi. 2021;55(11):1357–63.
Google Scholar
Karampatakis T, Tsergouli K, Behzadi P. Carbapenem-resistant Klebsiella pneumoniae: virulence factors, molecular epidemiology and latest updates in treatment options. Antibiotics (Basel, Switzerland). 2023;12(2):234.
Google Scholar
Li G, Shi J, Zhao Y, Xie Y, Tang Y, Jiang X, et al. Identification of Hypervirulent Klebsiella pneumoniae isolates using the string test in combination with Galleria mellonella infectivity. Eur J Clin Microbiol Infect Dis. 2020;39(9):1673–9.
Google Scholar
Russo TA, Olson R, Fang CT, Stoesser N, Miller M, MacDonald U, et al. Identification of biomarkers for differentiation of Hypervirulent Klebsiella pneumoniae from classical K. pneumoniae. J Clin Microbiol. 2018;56(9):e00776-00718.
Google Scholar
Yang P, Liu C, Wu Z, Zheng J, Yi J, Wu N, et al. Clinical outcomes, microbiological characteristics and risk factors for difficult-to-treat resistance to Klebsiella pneumoniae Infection. Infect Drug Resist. 2022;15:5959–69.
Google Scholar
Choby JE, Howard-Anderson J, Weiss DS. Hypervirulent Klebsiella pneumoniae – clinical and molecular perspectives. J Intern Med. 2020;287(3):283–300.
Google Scholar
Lee SS, Chen YS, Tsai HC, Wann SR, Lin HH, Huang CK, et al. Predictors of septic metastatic infection and mortality among patients with Klebsiella pneumoniae liver abscess. Clin Infect Dis. 2008;47(5):642–50.
Google Scholar
Li J, Ren J, Wang W, Wang G, Gu G, Wu X, et al. Risk factors and clinical outcomes of hypervirulent Klebsiella pneumoniae induced bloodstream infections. Eur J Clin Microbiol Infect Dis. 2018;37(4):679–89.
Google Scholar
Saki M, Amin M, Savari M, Hashemzadeh M, Seyedian SS. Beta-lactamase determinants and molecular typing of carbapenem-resistant classic and hypervirulent Klebsiella pneumoniae clinical isolates from southwest of Iran. Front Microbiol. 2022;13:1029686.
Google Scholar
Liu C, Du P, Zhao J, Li B, Wang C, Sun L, et al. Phenotypic and genomic characterization of virulence heterogeneity in multidrug-resistant ST11 Klebsiella pneumoniae during inter-host transmission and evolution. Infect Drug Resist. 2020;13:1713–21.
Google Scholar
Azoulay E, Russell L, Van de Louw A, Metaxa V, Bauer P, Povoa P, et al. Diagnosis of severe respiratory infections in immunocompromised patients. Intens Care Med. 2020;46(2):298–314.
Google Scholar
Di Pasquale MF, Sotgiu G, Gramegna A, Radovanovic D, Terraneo S, Reyes LF, et al. Prevalence and etiology of community-acquired pneumonia in immunocompromised patients. Clin Infect Dis. 2019;68(9):1482–93.
Google Scholar
Lemiale V, Resche-Rigon M, Azoulay E. Early non-invasive ventilation for acute respiratory failure in immunocompromised patients (IVNIctus): study protocol for a multicenter randomized controlled trial. Trials. 2014;15:372.
Google Scholar
Harada S, Aoki K, Yamamoto S, Ishii Y, Sekiya N, Kurai H, et al. Clinical and molecular characteristics of Klebsiella pneumoniae isolates causing bloodstream infections in Japan: occurrence of Hypervirulent infections in health care. J Clin Microbiol. 2019;57(11):e01206-01219.
Google Scholar
Russo TA, MacDonald U. The galleria mellonella infection model does not accurately differentiate between Hypervirulent and classical Klebsiella pneumoniae. mSphere. 2020;5(1):00850–00819.
Wang Z, Zhang L, Li S, Xu F, Han D, Wang H, et al. The relationship between hematocrit and serum albumin levels difference and mortality in elderly sepsis patients in intensive care units-a retrospective study based on two large database. BMC Infect Dis. 2022;22(1):629.
Google Scholar
Wiedermann CJ. Hypoalbuminemia as surrogate and culprit of infections. Int J Mol Sci. 2021;22(9):4496.
Google Scholar
Higashikawa T, Okuro M, Ishigami K, Mae K, Sangen R, Mizuno T, et al. Procalcitonin and albumin as prognostic biomarkers in elderly patients with a risk of bacterial infection. J Int Med Res. 2018;46(7):2606–14.
Google Scholar
Semler MW, Rice TW. Sepsis resuscitation: fluid choice and dose. Clin Chest Med. 2016;37(2):241–50.
Google Scholar
Rochwerg B, Alhazzani W, Sindi A, Heels-Ansdell D, Thabane L, Fox-Robichaud A, et al. Fluid resuscitation in sepsis: a systematic review and network meta-analysis. Ann Intern Med. 2014;161(5):347–55.
Google Scholar
Caironi P, Tognoni G, Masson S, Fumagalli R, Pesenti A, Romero M, et al. Albumin replacement in patients with severe sepsis or septic shock. N Engl J Med. 2014;370(15):1412–21.
Google Scholar
Li W, Sun G, Yu Y, Li N, Chen M, Jin R, et al. Increasing occurrence of antimicrobial-resistant hypervirulent (hypermucoviscous) Klebsiella pneumoniae isolates in China. Clin Infect Dis. 2014;58(2):225–32.
Google Scholar
Guo Y, Wang S, Zhan L, Jin Y, Duan J, Hao Z, et al. Microbiological and clinical characteristics of hypermucoviscous Klebsiella pneumoniae isolates associated with invasive infections in China. Front Cell Infect Microbiol. 2017;7:24.
Google Scholar
Liu C, Guo J. Hypervirulent Klebsiella pneumoniae (hypermucoviscous and aerobactin positive) infection over 6 years in the elderly in China: antimicrobial resistance patterns, molecular epidemiology and risk factor. Ann Clin Microbiol Antimicrob. 2019;18(1):4.
Google Scholar
Li L, Yuan Z, Chen D, Xie X, Zhang B. Clinical and microbiological characteristics of invasive and Hypervirulent Klebsiella pneumoniae Infections in a teaching hospital in China. Infect Drug Resist. 2020;13:4395–403.
Google Scholar
Shao C, Xin L, Mi P, Jiang M, Wu H. Phenotypic and molecular characterization of K54-ST29 Hypervirulent Klebsiella pneumoniae causing multi-system infection in a patient with diabetes. Front Microbiol. 2022;13: 872140.
Google Scholar
Lin YC, Cao X, Mo YC, Xie CP, Zhang YF, Li N, et al. Successful treatment of hypervirulent Klebsiella pneumoniae bacteremia with combination carbapenem and rifampicin. IDCases. 2021;26: e01276.
Google Scholar
Foo NP, Chen KT, Lin HJ, Guo HR. Characteristics of pyogenic liver abscess patients with and without diabetes mellitus. Am J Gastroenterol. 2010;105(2):328–35.
Google Scholar
Lin JC, Siu LK, Fung CP, Tsou HH, Wang JJ, Chen CT, et al. Impaired phagocytosis of capsular serotypes K1 or K2 Klebsiella pneumoniae in type 2 diabetes mellitus patients with poor glycemic control. J Clin Endocrinol Metab. 2006;91(8):3084–7.
Google Scholar
Yang F, Wang L, Zhao Q, Wu J, Jiang L, Sheng L, et al. Epidemiological features of Klebsiella pneumoniae infection in the hepatobiliary system of patients in Yantai, China, based on clinical and genetic analyses. Infect Drug Resist. 2022;15:3427–36.
Google Scholar
Huang MY, Chen CY, Chien JH, Wu KH, Chang YJ, Wu KH, et al. Serum procalcitonin and procalcitonin clearance as a prognostic biomarker in patients with severe sepsis and septic shock. Biomed Res Int. 2016;2016:1758501.
Google Scholar
Chen J, Yang Y, Yao H, Bu S, Li L, Wang F, et al. Prediction of prognosis in adult patients with Carbapenem-resistant Klebsiella pneumoniae infection. Front Cell Infect Microbiol. 2021;11: 818308.
Google Scholar
Siu LK, Yeh KM, Lin JC, Fung CP, Chang FY. Klebsiella pneumoniae liver abscess: a new invasive syndrome. Lancet Infect Dis. 2012;12(11):881–7.
Google Scholar
Pomakova DK, Hsiao CB, Beanan JM, Olson R, MacDonald U, Keynan Y, et al. Clinical and phenotypic differences between classic and hypervirulent Klebsiella pneumonia: an emerging and under-recognized pathogenic variant. Eur J Clin Microbiol Infect Dis. 2012;31(6):981–9.
Google Scholar
Yamamoto H, Iijima A, Kawamura K, Matsuzawa Y, Suzuki M, Arakawa Y. Fatal fulminant community-acquired pneumonia caused by hypervirulent Klebsiella pneumoniae K2-ST86: case report. Medicine. 2020;99(21): e20360.
Google Scholar
Li S, Yu S, Peng M, Qin J, Xu C, Qian J, et al. Clinical features and development of Sepsis in Klebsiella pneumoniae infected liver abscess patients: a retrospective analysis of 135 cases. BMC Infect Dis. 2021;21(1):597.
Google Scholar
Wang JH, Liu YC, Lee SS, Yen MY, Chen YS, Wang JH, et al. Primary liver abscess due to Klebsiella pneumoniae in Taiwan. Clin Infect Dis. 1998;26(6):1434–8.
Google Scholar
Hao Z, Duan J, Liu L, Shen X, Yu J, Guo Y, et al. Prevalence of community-acquired, Hypervirulent Klebsiella pneumoniae isolates in Wenzhou, China. Microbial Drug Resist (Larchmont, NY). 2020;26(1):21–7.
Google Scholar
Namikawa H, Yamada K, Sakiyama A, Imoto W, Yamairi K, Shibata W, et al. Clinical characteristics of bacteremia caused by hypermucoviscous Klebsiella pneumoniae at a tertiary hospital. Diagn Microbiol Infect Dis. 2019;95(1):84–8.
Google Scholar
Hwang JH, Handigund M, Hwang JH, Cho YG, Kim DS, Lee J. Clinical features and risk factors associated with 30-day mortality in patients with pneumonia caused by Hypervirulent Klebsiella pneumoniae (hvKP). Ann Lab Med. 2020;40(6):481–7.
Google Scholar
Gomez-Simmonds A, Greenman M, Sullivan SB, Tanner JP, Sowash MG, Whittier S, et al. Population structure of Klebsiella pneumoniae causing bloodstream infections at a New York City tertiary care hospital: diversification of multidrug-resistant isolates. J Clin Microbiol. 2015;53(7):2060–7.
Google Scholar
Sheng Z, Li J, Chen T, Zhu Y, Yu X, He X, et al. Clinical and Microbiological Characteristics of Klebsiella pneumoniae Bloodstream Infection in a Chinese Hospital: Hypervirulent and Multiclonal. Infect Drug Resist. 2022;15:3981–90.
Google Scholar
Liu YM, Li BB, Zhang YY, Zhang W, Shen H, Li H, et al. Clinical and molecular characteristics of emerging hypervirulent Klebsiella pneumoniae bloodstream infections in mainland China. Antimicrob Agents Chemother. 2014;58(9):5379–85.
Google Scholar
Liu C, Shi J, Guo J. High prevalence of hypervirulent Klebsiella pneumoniae infection in the genetic background of elderly patients in two teaching hospitals in China. Infect Drug Resist. 2018;11:1031–41.
Google Scholar
Li XJ, Wang QL, Feng JC, Guan XL, Chen ZJ, Hu B. Homology analysis and clinical infection characteristics of hypervirulent Klebsiella pneumonia. Zhonghua Yu Fang Yi Xue Za Zhi. 2021;55(8):945–51.
Google Scholar
Wu X, Shi Q, Shen S, Huang C, Wu H. Clinical and bacterial characteristics of Klebsiella pneumoniae affecting 30-day mortality in patients with bloodstream infection. Front Cell Infect Microbiol. 2021;11: 688989.
Google Scholar
Lu F, Ma D, Zhu W, Kong G, Wang X. Prognostic analysis of severe patients with bloodstream infection caused by Enterobacteriaceae bacteria. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2020;32(4):454–7.
Google Scholar
Wan Q, Ye Q, Su T, Zhou J. The epidemiology and distribution of pathogens and risk factors for mortality in liver transplant recipients with Gram negative bacteremia. Hepatogastroenterology. 2014;61(134):1730–3.
Google Scholar
Zhang Y, Zhao C, Wang Q, Wang X, Chen H, Li H, et al. High prevalence of Hypervirulent Klebsiella pneumoniae infection in China: geographic distribution, clinical characteristics, and antimicrobial resistance. Antimicrob Agents Chemother. 2016;60(10):6115–20.
Google Scholar
Liu C, Guo J. Characteristics of ventilator-associated pneumonia due to hypervirulent Klebsiella pneumoniae genotype in genetic background for the elderly in two tertiary hospitals in China. Antimicrob Resist Infect Control. 2018;7:95.
Google Scholar
Liao W, De Wang L, Li D, Du FL, Long D, Liu Y, et al. High prevalence of 16s rRNA methylase genes among Carbapenem-resistant Hypervirulent Klebsiella pneumoniae Isolates in a Chinese tertiary hospital. Microbial Drug Resist (Larchmont, NY). 2021;27(1):44–52.
Google Scholar
