Monthly Archives: August 2023

Genetic insights into resting heart rate and its role in cardiovascular disease

Abstract Resting heart rate is associated with cardiovascular diseases and mortality in observational and Mendelian randomization studies. The aims of this study are to extend the number of resting heart rate associated genetic variants and to obtain further insights in resting heart rate biology and its clinical consequences. A genome-wide meta-analysis of 100 studies in […]

COVID Cleared of Increasing Risk of Type 1 Diabetes in Kids?

COVID-19 infection didn’t appear to precipitate a diagnosis of type 1 diabetes in kids, a prospective multinational cohort study suggested. Researchers tested more than 4,500 adolescents every few months for type 1 diabetes, SARS-CoV-2 infection, and vaccination antibodies from January 2020 through December 2021. However, there was no difference among the 45 kids diagnosed with […]

Lymphohematopoietic cancer mortality among Korean semiconductor manufacturing workers

Female operators working in the semiconductor industry in South Korea experienced excess cancer mortality due to malignant neoplasms in the lymphoid, hematopoietic, and related tissues, especially leukemia. Female operators showed a 2.59-fold increased risk of mortality due to malignant neoplasms in the lymphoid, hematopoietic, and related tissues compared with the general population and 2.92-fold increased […]

Personalised nutrition app uncovers how hormonal cycle impacts blood sugar control

Austrian startup Hello Inside was developed to ’empower’ consumers ito reduce their energy spikes and crashes through better blood sugar control knowledge. Launched in May 2022, the app has hit the mark with female consumers who have been made aware of a change in their blood sugar responses throughout the month and have started to […]

Co-evolution of immunity and seasonal influenza viruses

Abstract Seasonal influenza viruses cause recurring global epidemics by continually evolving to escape host immunity. The viral constraints and host immune responses that limit and drive the evolution of these viruses are increasingly well understood. However, it remains unclear how most of these advances improve the capacity to reduce the impact of seasonal influenza viruses […]

Association between antenatal corticosteroids and risk of serious infection in children: nationwide cohort study

Abstract Objective To investigate the associations between exposure to antenatal corticosteroids and serious infection in children during the first three, six, and 12 months of life. Design Nationwide cohort study. Setting National Health Insurance Research Database, Birth Reporting Database, and Maternal and Child Health Database, 1 January 2008 to 31 December 2019, to identify all […]

OPG/RANK/RANKL axis relation to cardiac iron-overload in children with transfusion-dependent thalassemia

Abstract OPG/RANK/RANKL axis was reportedly involved in initiating various diseases, especially bone and cardiovascular diseases. This study aimed to assess the relationship between some OPG, RANK, and RANKL polymorphisms and alleles and iron-overload-induced cardiomyopathy in children with transfusion-dependent thalassemia (TDT). This study included 80 TDT children and 80 age and sex-matched controls. Real-time PCR was […]

Noninvasive disruption of the blood-brain barrier in the marmoset monkey

Abstract The common marmoset monkey (Callithrix jacchus) is a species of rising prominence in the neurosciences due to its small size, ease of handling, fast breeding, and its shared functional and structural brain characteristics with Old World primates. With increasing attention on modeling human brain diseases in marmosets, understanding how to deliver therapeutic or neurotropic […]

Alzheimer’s Disease Market Predicted to Surge at a CAGR of 20% During the Study Period (2019–2032), Assesses DelveInsight

New York, USA, Aug. 02, 2023 (GLOBE NEWSWIRE) — Alzheimer’s Disease Market Predicted to Surge at a CAGR of 20% During the Study Period (2019–2032), Assesses DelveInsight The Alzheimer’s disease market size is projected to grow significantly during the forecast period (2023–2032) owing to the launch of upcoming therapies and the increasing prevalence of the […]

Two-sample Mendelian randomization study does not reveal a significant relationship between cytomegalovirus (CMV) infection and autism spectrum disorder

ASD affects people worldwide and brings both health and economic burdens. As a widely known virus affecting the CNS in paediatric patients, CMV has long been suggested as a risk factor for ASD, yet no definite evidence has been found. To investigate whether CMV infection has a causal relationship with ASD, we conducted 3 MR […]