Infection
Human skin organoids are valid models of mpox virus infection
19
Oct
Oct
Human skin organoids are susceptible to mpox virus infection and support infectious virus production. Treatment of infected skin organoids with the antiviral drug tecovirimat can inhibit infectious virus production and prevent host transcriptome rewiring. Thus, skin-organoid-based models are robust for studying mpox virus infection and testing therapeutics.
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This is a summary of: Li, P. et al. Mpox virus infection and drug treatment modelled in human skin organoids. Nat. Microbiol. https://doi.org/10.1038/s41564-023-01489-6 (2023).
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Human skin organoids are valid models of mpox virus infection.
Nat Microbiol (2023). https://doi.org/10.1038/s41564-023-01490-z
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Published: 19 October 2023
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DOI: https://doi.org/10.1038/s41564-023-01490-z
