Cytogenetic Systems Industry is forecasted to secure a value of US$ 5,327.8 Million by 2032

Global Cytogenetic systems industry demand is anticipated to be valued at US$ 1,688.5 Million in 2022, forecast to grow at a CAGR of 11.0% to be valued at US$ 5,327.8 Million from 2022 to 2032. Growth is attributed to the increase in incidence of genetic disorders and cancer.

The major techniques of cytogenetic testing include fluorescence in-situ hybridization, multiplex-fluorescence in situ hybridization, comparative genomic hybridization and flow cytometry. The samples for the chromosomal analysis can be collected from peripheral blood, bone marrow, lymphomas and solid tumors. Under the technique of fluorescence in-situ hybridization, fluorescent molecules are developed to bind directly or via an intermediate molecule to DNA.

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In addition to the diagnosis of disease, cytogenetics involve applications such as gene mapping, marker chromosome identification, total chromosome analysis, translocation analysis, unique sequence DNA detection, microdeletion syndrome analysis and gene amplification analysis.

Cytogenetic systems industry: Drivers and Restraints

The key contributor to the growth of global Cytogenetic systems industry is rising demand of early diagnosis of severe life threatening diseases such as cancer and diagnosis of disorders due to chromosomal anomalies in developing embryos. Moreover, expansion of geriatric population pool, rising exposure to dangerous chemicals and ultraviolet rays, increase in numbers of people adopting bad habits such as smoking and drinking and the sedentary lifestyle is fuelling the market growth.

There are some factors which may slow down the market growth rate including technical limitations and complexities associated with the equipment, lack of awareness about advanced technological methodologies especially in low and middle income countries and high cost of sophisticated devices.

Cytogenetic systems industry: Overview

Global cytogenetic systems industry is highly fragmented with the presence of multiple players. Several collaborations and acquisitions focused on cytogenetic products have been reported recently such as Biological Industries USA, Inc. (BIUSA) collaborated with Rainbow Scientific, Inc.  to co-promote and sell BI-USA’s range of cytogenetic products, Roche and PerkinElmer entered into a new agreement for distribution of a PerkinElmer’s cytogenetic system and BioDot and ADS Biotech teamed up to market the Cell Writer Workstation in Europe.

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According to the WHO data, around 250,000 families in the USA are affected by Down syndrome, 20-30% of all infant deaths across the globe are due to genetic disorders and 30-50% of post-neonatal deaths are due to congenital malformations.

According to the statistics of the International Agency for Research on Cancer (IARC), in 2012, around 14.1 million new cancer cases and 8.2 million cancer deaths were reported worldwide. The numbers of new cancer cases and deaths due to cancers are expected to grow to 21.7 million and 13 million by 2030. The future burden may be even larger because of the adoption of sedentary lifestyles and bad habits such as smoking, poor diet, physical inactivity in developing countries.

Cytogenetic systems industry: Key Players

Some of the players in the global Cytogenetic systems industry include ADS Biotec Inc., Genial Genetics, Laboratory Imaging s.r.o., MetaSystems, Agilent Technologies, Cytocell Ltd, Leica Biosystems Nussloch GmbH, Applied Spectral Imaging, Irvine Scientifi­c, PerkinElmer Inc., Bio-Rad Laboratories, Inc. and Abbott Laboratories.

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Cytogenetic systems industry: Segmentation

Global Cytogenetic systems industry has been segmented on the basis of technologies, applications, end users and region.

Based on technologies, the global Cytogenetic systems industry is segmented into:

• Flow cytometry
• Fluorescence In Situ Hybridization (FISH)
• Multiplex- Fluorescence In Situ Hybridization (M-FISH)
• Comparative Genomic Hybridization (CGH)

Based on applications, the global cytogenetic systems industry is segmented into:

• Genetic Disorders
• Neoplastic Diseases
• Personalized Medicine
• Others

Based on end users, the global Cytogenetic systems industry is segmented into:

• Hospitals
• Clinics
• Diagnostic Laboratory Centers
• Research Institutes

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