Congenital disorders
North America Gene Therapy Market Size, Share, Trends, Development Strategies, Competitive Scenario
Oct
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The increasing research in gene therapy and its techniques and development is expected to boost market growth further. However, the ethical and safety concerns while performing the method is expected to hamper the growth of the North America gene therapy market in the forecast period. Increasing demand for gene therapy, an emerging and advanced field in genetic engineering and healthcare, is expected to give opportunities to the market to enhance the treatment and diagnostic approaches.
The growing demand for better quality healthcare for cancers and genetic disorders is expected to boost the market’s growth. However, the high cost of diagnostics and the lack of skilled and certified professionals are expected to challenge market growth.
Data Bridge Market Research analyzes that the North America gene therapy market is expected to reach USD 13,418.96 million by 2030, at a CAGR of 18.8% during the forecast period. Product accounts for the most significant type segment in the market due to the growing use of exosome research products in diagnostics and therapeutics.
Fundamental Aim of this Market Report
- Factors influencing This Market Size and growth rate.
- Major alterations to this market in the near future.
- Notable Market rivals around the world.
- Future Scope and Product Outlook
- Future-promising emerging markets.
- The Market Presents Difficult Challenges and Threats.
Market Overview:
Gene therapy is a medical strategy that addresses the underlying genetic issue in order to treat or prevent disease. Instead of utilising drugs or surgery, gene therapy procedures allow doctors to treat a problem by changing a person’s genetic composition. A select few disorders, including an eye condition called Leber congenital amaurosis and a muscle condition called spinal muscular atrophy, are being treated with gene therapy. To ensure that they will be secure and efficient, many other gene therapies are undergoing study. Medical professionals aim to soon apply the promising technique of genome editing to cure human illnesses.
The ability to successfully transport a therapeutic gene to a target cell is the most important prerequisite for gene therapy to be successful. Once transported, that gene must go to the cell wall’s nucleus, where it will serve as a model for making protein molecules. The principal therapeutic action is then produced by the protein. For instance, cell destruction might be used in the treatment of tumours, whereas cell preservation might be used in the case of neurodegenerative illness. However, strict regulations and standards for the approval and commercialization of products is expected to restrain the market growth.
Drivers
- Novel approaches of gene therapy
Gene therapy has brought permanent cures for ailments that were previously simply temporary treatments. For a very long period, gene therapy did not work; however, in recent years, effective and long-lasting treated cases have been recorded. For a wide range of hereditary illnesses, including blood abnormalities, immunological deficiencies, vision issues, nerve cell regeneration, metabolic disorders, and different types of cancer, promising outcomes have been attained.
With more specificity and fewer side effects, gene therapy has the potential to be a customized medicine that can “cure” a variety of diseases. Gene therapy generally refers to the transfer of genetic material to treat an illness, or at the very least, to enhance a patient’s clinical condition. Using viruses as genetic vectors to deliver the desired gene to the target cells is one method of how gene therapy functions. These vectors are classified as RNA-based or DNA-based viral vectors depending on the type of genome they contain.
The majority of experts concur that gene therapy has the potential to be the most intriguing use of DNA research to date. A simple intravenous injection of a gene transfer agent may one day be used to administer genes as medicine, seeking out target cells for stable, site-specific chromosomal integration and subsequent gene expression. It is predicted that there would be a need for gene therapy using revolutionary techniques that are being tested by researchers around the world and incorporated into conventional treatment is expected to act as driver for the growth of North America gene therapy market
- Increasing prevalance of genetic disorders
A sizable share of prenatal and neonatal mortality in several nations in the Region is caused by genetic and congenital diseases. Many multifactorial ailments are often caused by genetic factors as well. Gene alterations that are essentially present in every cell in the body cause many hereditary diseases. These illnesses thus frequently impact many bodily systems, and the majority cannot be treated.
For instance,
- The Department of Health indicated that roughly six out of ten people will be impacted by an ailment that has some genetic ties, according to the Government of Western Australia. Genetic disorders can range from minor to very severe. Between 3 and 5% of newborns born in Western Australia have genetic disorders or birth abnormalities
Mutations, exposure to chemicals and radiation, among other things, can all result in genetic disorders. Although some ailments have been treated with gene therapy, the majority of treatment plans for genetic disorders do not change the underlying genetic abnormality. For this, the prevalence of genetic abnormalities is significantly rising across all age groups and practically all geographic areas are expected to act as a driver for the growth of North America gene therapy market.
Recent Developments
- In December 2022 Kite Pharma, Inc., and Daiichi Sankyo Co., Ltd. announced that the Japan Ministry of Health, Labour and Welfare (MHLW) has approved Yescarta (axicabtagene ciloleucel), a chimeric antigen receptor (CAR) T-cell therapy, for the initial treatment of patients with relapsed/refractory large B-cell lymphoma (R/R LBCL): diffuse large B-cell lymphoma, primary mediastinal large B-cell lymphoma, transformed follicular lymphoma, and high-grade B-cell lymphoma. Only patients who have not previously had a transfusion of CAR T cells directed against the CD19 antigen should be treated with Yescarta
- In December, Ferring Pharmaceuticals announced the U.S. Food and Drug Administration (FDA) approved Adstiladrin (nadofaragene firadenovec-vncg), a novel adenovirus vector-based gene therapy, for the treatment of adult patients with high-risk, Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without papillary tumors. This has helped the company to expand their product portfolio
North America gene therapy market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in R&D, new market initiatives, production sites and facilities, company strengths and weaknesses, product launch, product approvals, product width and breath, application dominance, product type lifeline curve. The above data points provided are only related to the company’s focus on the North America gene therapy market.
Some of the major players operating in the North America gene therapy market are:, Novartis AG, Kite Pharma (a subsidiary of Gilead Sciences, Inc.), uniQure NV, Oxford Biomedica, Spark Therapeutics, Inc., SIBONO, bluebird bio, Inc., Shanghai Sunway Biotech Co. Ltd., Biogen, Dendreon Pharmaceuticals LLC., Amgen Inc., AnGes, Inc. and Enzyvant Therapeutics GmbHAudubon Bioscience, among others.
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North America Gene Therapy Market Scope
BY VECTOR TYPE
- Viral Vector
- Non-Viral Vector
On the basis of vector type, the North America gene therapy market is segmented into viral and non-viral vector.
BY METHOD
- Ex-Vivo
- In-Vivo
On the basis of method, the North America gene therapy market is segmented into ex vivo and in vivo.
BY APPLICATION
- Oncological Disorders
- Cardiovascular Diseases
- Infectious Disease
- Rare Diseases
- Neurological Disorders
- Other Diseases
On the basis of application, the North America gene therapy market is segmented into oncological disorders, cardiovascular diseases, infectious diseases, rare diseases, neurological disorders, and other diseases.
BY END USER
- Cancer Institutes
- Hospitals
- Research Institutes
- Others
Key highlights of this Market report:
- Growth rate
- Remuneration prediction
- Consumption graph
- Market concentration ratio
- Secondary industry competitors
- Competitive structure
- Major restraints
- Market drivers
- Regional bifurcation
- Competitive hierarchy
- Current market tendencies
- Market concentration analysis
What benefits does the DBMR study is going to provide?
- Latest industry influencing trends and development scenario
- Open up New Markets
- To Seize powerful market opportunities
- Key decision in planning and to further expand market share
- Identify Key Business Segments, Market proposition & Gap Analysis
- Assisting in allocating marketing investments
Table of Contents:
- Introduction
- Market Segmentation
- Executive Summary
- Premium Insights
- Market Regulations
- Market Overview
Continued…
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