Monthly Archives: October 2023

Sex-related differences for uric acid in the prediction of cardiovascular events in essential hypertension. A population prospective study

Mazzali M, Hughes J, Kim YG, Jefferson JA, Kang DH, Gordon KL, et al. Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism. Hypertension. 2001;38:1101–6. https://doi.org/10.1161/hy1101.092839. Article  CAS  PubMed  Google Scholar  Feig DI, Johnson RJ. Hyperuricemia in childhood primary hypertension. Hypertension. 2003;42:247–52. https://doi.org/10.1161/01.HYP.0000085858.66548.59. Article  CAS  PubMed  Google Scholar  Johnson RJ, […]

IBD patients at risk of serious infection, even when disease is mild

Newswise — Inflammatory bowel disease (IBD) is an independent risk factor for serious infection, even at very low levels of gastrointestinal inflammation. This has been shown by a study at the University of Gothenburg. IBD is an umbrella term for chronic inflammatory bowel diseases, with a population prevalence of around 0.5%. The main types of […]

Association of serum copper (Cu) with cardiovascular mortality and all-cause mortality in a general population: a prospective cohort study

(WHO) WHO. Cardiovascular diseases (CVDs). 2017;2023. Ding D, Lawson KD, Kolbe-Alexander TL, Finkelstein EA, Katzmarzyk PT, van Mechelen W, Pratt M. The economic burden of Physical Inactivity: a global analysis of major non-communicable Diseases. Lancet. 2016;388:1311–24. PubMed  Google Scholar  Li Z, Fan Y, Tao C, Yan W, Huang Y, Qian H, Xu Q, Wan T, […]

The mechanisms of nerve injury caused by viral infection in the occurrence of gastrointestinal motility disorder-related diseases

Ouyang A, Locke GR 3. rd. Overview of neurogastroenterology-gastrointestinal motility and functional GI disorders: classification, prevalence, and epidemiology. Gastroenterol Clin North Am. 2007;36:485 – 98, vii. Mittal R, Vaezi MF. Esophageal motility Disorders and gastroesophageal reflux disease. N Engl J Med. 2020;383:1961–72. CAS  PubMed  Google Scholar  Thapar N, Saliakellis E, Benninga MA, Borrelli O, Curry […]

Signs of ear infections in infants and kids

Caring for a little one often requires some detective work. Are they fussing because they’re hungry? Wet diaper? Sleepy? If none of these seem to be the case, it could be an ear infection. “Childhood ear infections are extremely common,” explains Aileen Wertz, MD, a pediatric ear, nose and throat (ENT) specialist at Geisinger. “The […]

Phase III Win in Schizophrenia; Bipolar Blood Test; How Do Psychedelics Work?

The 50-mg dose of the investigational drug brilaroxazine significantly reduced symptoms of schizophrenia in adults within 4 weeks in the phase III RECOVER trial, developer Reviva Pharmaceuticals announced. Severe mental illness was linked with a 50% higher risk of death following COVID infection. (British Journal of Psychiatry) A simple blood test may bolster the differential […]

VIDEO: Relationship between hyperphosphatemia, cardiovascular conditions

Editor’s note: This is an automatically generated transcript. Please notify [email protected] if there are concerns regarding accuracy of the transcription. I think the clinicians should really be in a position to emphasize the importance of controlling high levels of phosphorus in blood. They should know that this is an important risk factor for mortality and […]

Cardiovascular and VTE Risk With JAK Inhibitors in Immune-Mediated Inflammatory Skin Diseases

Key Points Question  Are Janus kinase (JAK) inhibitors associated with higher risk of all-cause mortality, major adverse cardiovascular events (MACE), and venous thromboembolism (VTE) when used for a dermatologic indication? Findings  In this systematic review and meta-analysis of 35 randomized clinical trials containing over 20 000 patients with dermatologic conditions, no significant difference was found between […]