Elisabeth Mahase The BMJ Cancer alliances across England are preparing to pilot the multi-cancer early detection (MCED) test Galleri—a blood test that detects abnormal DNA from cancer cells—from next year after NHS England agreed to buy one million of the tests. The Grail interim implementation pilot will target areas of higher deprivation and offer the […]
Whole-genome sequencing of Clostridioides difficile from a densely sampled intensive care unit (ICU) population showed that many of these patients harbor toxigenic C. difficile. This carriage did not lead to high levels of cross-transmission but was associated with a greatly increased risk of developing clinically overt C. difficile infection. This is a preview of subscription […]
Abstract Cardiovascular disease (CVD) is one of the leading causes of premature retirement. However, the relationship between CVD risk factors and workforce participation is not well known. We studied the relationship between midlife CVD risk, age at retirement, work-loss years, and survival in retirement. Middle-aged Finnish men (initial n = 3490, mean age = 47.8 years) were assessed for CVD […]
Carbapenem-resistant Enterobacterales (CREs) are a dominant threat to patient health in healthcare settings worldwide. CRE strains consistently have limited therapeutic options, often associated with increased toxicities, and require prolonged treatment, leading to a higher cost burden than carbapenem-susceptible strains [9]. In this study, 61.9% of carbapenem-resistant isolates were K. pneumoniae. Compared to each other, 38.1% […]
Abstract Lower respiratory tract infections caused by Streptococcus pneumoniae (Spn) are a leading cause of death globally. Here we investigate the bronchial epithelial cellular response to Spn infection on a transcriptomic, proteomic and metabolic level. We found the NAD+ salvage pathway to be dysregulated upon infection in a cell line model, primary human lung tissue […]
Abstract Purpose Magnetic resonance imaging (MRI) has deeply altered the prostate biopsy strategy to detect prostate cancer. However, it is still debatable whether the detection rate differs between transrectal (TR) and transperineal (TP) MRI-targeted biopsy (MRI-TB). To compare the effectiveness of these two methods for detecting both overall prostate cancer (PCa) and clinically significant PCa […]
Starting Monday, newborns in New York will be screened for congenital cytomegalovirus — a virus that can cause deafness or other health complications for babies born with the affliction. The free test is now part of a baby’s routine newborn screening. New York will be the second state to screen all babies for the virus after Minnesota, the state […]
By far the greatest predictor of cardiovascular disease over 10 years is age. Photo / Getty Images Question: My husband has researched LDL cholesterol (Nutrition, August 19) and says we’re not getting the whole story. Apparently, there is bad and “not so bad” LDL, but blood tests give only one result unless Advertisement Advertise with NZME.
Credit: Unsplash/CC0 Public Domain Exposure to natural light could help treat and prevent type 2 diabetes, new research presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Hamburg, Germany (2–6 Oct), suggests. “The misalignment of our internal circadian clock with the demands of a 24/7 society is associated […]
Research finds diabetes tests calibrated at male blood sugar readings Almost 35,000 women may have been mistakenly told they do not have diabetes Changing blood sugar cut-off could increase female diagnosis by 17% per year By Victoria Allen Science Editor Published: 17:50 EDT, 1 October 2023 | Updated: 17:50 EDT, 1 October 2023