Monthly Archives: October 2023

Epidemiology and clinical severity of the serotypes of human parainfluenza virus in children with acute respiratory infection

Pneumonia Etiology Research for Child Health Study G. Causes of severe Pneumonia requiring hospital admission in children without HIV Infection from Africa and Asia: the PERCH multi-country case-control study. Lancet. 2019;394(10200):757–79. Article  Google Scholar  Falsey AR. Current management of parainfluenza pneumonitis in immunocompromised patients: a review. Infect Drug Resist. 2012;5:121–7. Article  PubMed  PubMed Central  Google […]

Post-acute Care Market Worth $1.37 Billion, Globally, Billion by 2030 – Exclusive Report by The Insight Partners

Pune, India, Oct. 26, 2023 (GLOBE NEWSWIRE) — Post-acute care encompasses a broad range of services the patient gets after hospitalization. Sometimes, these services are provided as an alternative to acute care hospitalization, depending upon the type of disease or injury. It could include a stay in an acute care facility, home health care, or […]

Karyopharm to Report Third Quarter 2023 Financial Results on November 2, 2023

— Conference Call Scheduled for Thursday, November 2, 2023, at 8:00 a.m. ET — NEWTON, Mass., Oct. 26, 2023 /PRNewswire/ — Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced it will report third quarter 2023 financial results on Thursday, November 2, 2023. Karyopharm’s management team will host a […]

FHL1 promotes chikungunya and o’nyong-nyong virus infection and pathogenesis with implications for alphavirus vaccine design

Abstract Arthritogenic alphaviruses are positive-strand RNA viruses that cause debilitating musculoskeletal diseases affecting millions worldwide. A recent discovery identified the four-and-a-half-LIM domain protein 1 splice variant A (FHL1A) as a crucial host factor interacting with the hypervariable domain (HVD) of chikungunya virus (CHIKV) nonstructural protein 3 (nsP3). Here, we show that acute and chronic chikungunya […]

Bi-allelic truncating variants in CASP2 underlie a neurodevelopmental disorder with lissencephaly

Abstract Lissencephaly (LIS) is a malformation of cortical development due to deficient neuronal migration and abnormal formation of cerebral convolutions or gyri. Thirty-one LIS-associated genes have been previously described. Recently, biallelic pathogenic variants in CRADD and PIDD1, have associated with LIS impacting the previously established role of the PIDDosome in activating caspase-2. In this report, […]

Deep learning models of ultrasonography significantly improved the differential diagnosis performance for superficial soft-tissue masses: a retrospective multicenter study

This study evaluated the performance of a DLM system in the differential diagnosis of superficial soft-tissue masses, especially its value for less experienced and experienced radiologists. The DLM-assisted diagnosis was significantly helpful for the two radiologists. DLM-1 and DLM-2 are two deep learning diagnostic models. DLM-1 was trained to distinguish between benign and malignant masses, […]

Atlanta mother of three says flesh-eating bacterial infection made her a quadruple amputee

Mom survives flesh-eating bacterial infection Kiyahki Bivins is a mother of three who has had to fight for her life. She said she spent three months in Peidmont Hospital after mysteriously contracting a flesh-eating bacterial infection. Eventually, the sickness caused her to lose limbs and fingers. She tells the FOX 5 Medical Team she’s finally […]

A less invasive approach to a heart valve disease

Due to shared lifestyle risk factors, aortic stenosis can sometimes be mistaken for myocardial infarction, more commonly known as a heart attack. The latter often arises when blood flow to the heart is reduced or blocked by atherosclerosis, resulting in poor oxygen supply to the heart muscle. Without the prompt restoration of blood flow, the […]