Infection
Sero-prevalence of syphilis infection among people living with HIV in Sierra Leone: a cross-sectional nationwide hospital-based study
Nov
Global progress report on HIV, viral hepatitis and other sexually transmitted infections. (2021). Available at: https://www.who.int/data/gho/data/themes/topics/data-on-syphilis. (Accessed 2 June 2023).
Newman L, Kamb M, Hawkes S, Gomez G, Say L, Seuc A, Broutet N. Global estimates of Syphilis in pregnancy and associated adverse outcomes: analysis of multinational antenatal surveillance data. PLoS Med. 2013;10(2):e1001396. https://doi.org/10.1371/journal.pmed.1001396. Epub 2013 Feb 26. PMID: 23468598; PMCID: PMC3582608.
Google Scholar
Tripathy DM, Gupta S, Vasudevan B. Resurgence of Syphilis, the great imitator. Med J Armed Forces India. 2022;78(2):131–5. https://doi.org/10.1016/j.mjafi.2022.03.004. Epub 2022 Mar 23. PMID: 35463552; PMCID: PMC9023770.
Google Scholar
Orbe-Orihuela YC, Sánchez-Alemán MÁ, Hernández-Pliego A, Medina-García CV, Vergara-Ortega DN. Syphilis as re-emerging disease, antibiotic resistance, and vulnerable population: global systematic review and meta-analysis. Pathogens. 2022;11:1546.
Google Scholar
Palacios R, Jimenez-Onate F, Aguilar M, et al. Impact of Syphilis Infection on HIV viral load and CD4 cell counts in HIV-infected patients. J Acquir Immune Defic Syndr. 2007;44:356–9.
Google Scholar
Koga I, Odawara T, Matsuda M, Sugiura W, Goto M, Nakamura T, Iwamoto A. Analysis of HIV-1 sequences before and after co-infecting Syphilis. Microbes Infect. 2006;8(14–15):2872–9.
Google Scholar
Global health sector. strategies on, respectively, HIV, viral hepatitis and sexually transmitted infections for the period 2022–2030. Available at: https://www.who.int/teams/global-hiv-hepatitis-and-stis-programmes/strategies/global-health-sector-strategies#:~:text=The%20strategies%20aim%20to%20end,WHO’s%20General%20Programme%20of%20Work. (Accessed 2 June 2023).
Bourouache M, Mimouni R, Nejmeddine M, Chadli S, Benlmeliani F, Sardi J, Malmoussi M, Ouagari Z, Basbassi ME, Aghrouch M. The prevalence of Syphilis in HIV-seropositive patients: a retrospective study at the regional hospital in Agadir, Morocco. Pan Afr Med J. 2019;33:252.
Google Scholar
Mamoojee Y, Tan G, Gittins S, Sarfo S, Stephenson L, Carrington D, Bedu-Addo G, Phillips R, Appiah LT, Chadwick D. Diagnosis of treponemal co-infection in HIV-infected West Africans. Trop Med Int Health. 2012;17(12):1521–6. https://doi.org/10.1111/j.1365-3156.2012.03090.x. xEpub 2012 Sep 20 PMID: 22994205.
Google Scholar
Lee NY, Chen YC, Liu HY, Li CY, Li CW, Ko WC, Ko NY. Increased repeat Syphilis among HIV-infected patients: a nationwide population-based cohort study in Taiwan. Med (Baltim). 2020;99(28):e21132. https://doi.org/10.1097/MD.0000000000021132. PMID: 32664143; PMCID: PMC7360277.
Google Scholar
Lang R, Read R, Krentz HB, Ramazani S, Peng M, Gratrix J, Gill MJ. Increasing incidence of Syphilis among patients engaged in HIV care in Alberta, Canada: a retrospective clinic-based cohort study. BMC Infect Dis. 2018;18(1):125. https://doi.org/10.1186/s12879-018-3038-4. PMID: 29534681; PMCID: PMC5851255.
Google Scholar
Sarkodie F, Owusu-Dabo E, Hassall O, Bates I, Bygbjerg IC, Ullum H. Recall of symptoms and treatment of Syphilis and yaws by healthy blood donors screening positive for Syphilis in Kumasi, Ghana. Int J Infect Dis. 2016;50:72–4. Epub 2016 Aug 12. PMID: 27531187.
Google Scholar
Sierra Leone Demographic Health Survey (SLDHS). 2019. Available at: https://dhsprogram.com/pubs/pdf/PR122/PR122.pdf. (Accessed on 3 June 2023).
UNAIDS Country progress report – Sierra Leone. Available at: https://www.unaids.org/sites/default/files/country/documents/SLE_2020_countryreport.pdf. (Accessed 2 June 2023).
Djibo DA, Sahr F, McCutchan JA, Jain S, Araneta MRG, Brodine SK, Shaffer RA. Prevalence and risk factors for human immunodeficiency virus (HIV) and Syphilis Infections among Military Personnel in Sierra Leone. Curr HIV Res. 2017;15(2):128–36. https://doi.org/10.2174/1570162X15666170517101349. PMID: 28521722.
Google Scholar
Yambasu EE, Reid A, Owiti P, Manzi M, Murray MJS, Edwin AK. Hidden dangers-prevalence of blood borne pathogens, Hepatitis B, C, HIV and Syphilis, among blood donors in Sierra Leone in 2016: opportunities for improvement: a retrospective, cross-sectional study. Pan Afr Med J. 2018;30:44. https://doi.org/10.11604/pamj.2018.30.44.14663. PMID: 30167071; PMCID: PMC6110571.
Google Scholar
Yendewa GA, Lakoh S, Yendewa SA, Bangura K, Lawrence H, Patiño L, Jiba DF, Vandy AO, Murray MJS, Massaquoi SP, Deen GF, Sahr F, Hoffmann CJ, Jacobson JM, Poveda E, Aguilera A, Salata RA. Prevalence of Hepatitis B surface antigen and serological markers of other endemic Infections in HIV-infected children, adolescents and pregnant women in Sierra Leone: a cross-sectional study. Int J Infect Dis. 2021;102:45–52. Epub 2020 Sep 28. PMID: 33002619.
Google Scholar
GoSL SLMTDP Development-Documents-National-Development-Plan-2019-23-47099. 2018. Available online: https://www.imf.org/en/Publications/CR/Issues/2019/07/09/Sierra-Leone-Economic-Development-DocumentsNational-Development-Plan-2019-23-47099. [(Accessed on 14 January 2022)].
SSL. 2015: Sierra Leone Population Census. Available online: https://www.statistics.sl/images/StatisticsSL/Documents/Census/2015/sl_2015_phc_thematic_report_on_pop_structure_and_pop_distribution.pdf. (Accessed on 14 January 2022).
MICS 2017: Sierra leone multiple indicator cluster survey. 2017. Available online: https://www.statistics.sl/images/StatisticsSL/Documents/sierra_leone_mics6_2017_report.pdf. (Accessed on 14 January 2022).
Global health sector. strategies on, respectively, HIV, viral hepatitis and sexually transmitted infections for the period 2022–2030. Available at: https://iris.who.int/bitstream/handle/10665/360348/9789240053779-eng.pdf?sequence=1. Accessed 16 October 2023).
United Nations Sustainable Development Goals. [(Accessed on 16 October 2023)]. Available online: https://sdgs.un.org/goals.
Shimelis T, Lemma K, Ambachew H, et al. Syphilis among people with HIV Infection in southern Ethiopia: sero-prevalence and risk factors. BMC Infect Dis. 2015;15:189. https://doi.org/10.1186/s12879-015-0919-7.
Google Scholar
Uneke C, Ogbu O, Alo M, Obaji A. Syphilis serology in HIV-positive and HIV-negative nigerians: the public health significance. Online Journal of Health & Allied Sciences; 2006.
Adawaye C, Souleymane AO, Fouda AA, Djarma O, Cournil A, Tuaillon E, Mennechet FJD. Syphilis diagnosis and serological response to Benzathine Penicillin G among patients attending HIV clinics in N’Djaména, Chad. Int J Infect Dis. 2021;108:461–4. Epub 2021 May 26. PMID: 34051363.
Google Scholar
Haule A, Msemwa B, Mgaya E, Masikini P, Kalluvya S. Prevalence of Syphilis, neurosyphilis and associated factors in a cross-sectional analysis of HIV infected patients attending Bugando Medical Centre, Mwanza, Tanzania. BMC Public Health. 2020;20(1):1862. https://doi.org/10.1186/s12889-020-09984-9. PMID: 33276749; PMCID: PMC7718654.
Google Scholar
Yang B, Hallmark CJ, Huang JS, Wolverton ML, McNeese-Ward M, Arafat RR. Characteristics and risk of syphilis diagnosis among HIV-infected male cohort: a population-based study in Houston. Texas Sex Transm Dis. 2013;40(12):957–63. https://doi.org/10.1097/OLQ.0000000000000056. PMID: 24220358.
Google Scholar
Adolf R, Bercht F, Aronis ML, Lunardi LW, Schechter M, Sprinz E. Prevalence and risk factors associated with Syphilis in a cohort of HIV positive individuals in Brazil. AIDS Care. 2012;24(2):252–8. Epub 2011 Jul 25. PMID: 21780954.
Google Scholar
Mboowa G, Inda D. Seroprevalence of Syphilis among Human Immunodeficiency Virus Positive Individuals Attending Immune Suppressed Syndrome Clinic at International Hospital Kampala, Uganda. Int STD Res Rev. 2015;3:84–90. https://doi.org/10.9734/ISRR/2015/18965.
Google Scholar
Nakagawa F, May M, Phillips A. Life expectancy living with HIV: recent estimates and future implications. Current Opinion in Infectious Diseases. 2013;26(1):p 17–25. | https://doi.org/10.1097/QCO.0b013e32835ba6b1.
Tura JB, Ayalew J, Moreda AB, et al. Prevalence of Syphilis and associated factors among female sex workers in Ethiopia: findings from a multilevel analysis of a national bio-behavioral survey. BMC Public Health. 2023;23:809. https://doi.org/10.1186/s12889-023-15745-1.
Google Scholar
Guo YL, Zhou JB, Hao C, Huan XP, Shi TP, Wang JT, Zhen S, Yin YP. [Comparative analysis on both high risk behaviours, Infection of HIV and Syphilis between married and unmarried men who have sex with men]. Zhonghua Liu Xing Bing Xue Za Zhi. 2013;34(1):19–23. Chinese. PMID: 23648243.
Google Scholar
Hu Q, Xu J, Zou H, et al. Risk factors associated with prevalent and incident Syphilis among an HIV-infected cohort in Northeast China. BMC Infect Dis. 2014;14:658. https://doi.org/10.1186/s12879-014-0658-1.
Google Scholar
Rekart ML, Ndifon W, Brunham RC, Dushoff J, Park SW, Rawat S, Cameron CE. A double-edged sword: does highly active antiretroviral therapy contribute to Syphilis incidence by impairing immunity to Treponema pallidum? Sex Transm Infect. 2017;93(5):374–8. https://doi.org/10.1136/sextrans-2016-052870. Epub 2017 Jan 16. PMID: 28093460; PMCID: PMC5537507.
Google Scholar
Crepaz N, Marks G, Liau A, et al. Prevalence of unprotected anal intercourse among HIV-diagnosed MSM in the United States: a meta-analysis. AIDS. 2009;23:1617–29. https://doi.org/10.1097/QAD.0b013e32832effae.
Google Scholar
Stephenson JM, Imrie J, Davis MMD, et al. Is use of antiretroviral therapy among homosexual men associated with increased risk of transmission of HIV Infection? Sex Transm Infect. 2003;79:7–10. https://doi.org/10.1136/sti.79.1.7.
Google Scholar
Remien RH, Halkitis PN, O’Leary A, et al. Risk perception and sexual risk behaviors among HIV-positive men on antiretroviral therapy. AIDS Behav. 2005;9:167–76. https://doi.org/10.1007/s10461-005-3898-7.
Google Scholar
Chen SC, Wang ST, Chen KT, Yan TR, Tang LH, Lin CC, Yen SF. Analysis of the influence of therapy and viral suppression on high-risk sexual behaviour and sexually transmitted infections among patients infected with human immunodeficiency virus in Taiwan. Clin Microbiol Infect. 2006;12(7):660–5.
Vu TMT, Boggiano VL, Tran BX, Nguyen LH, Tran TT, Latkin CA, Ho CSH, Ho RCM. Sexual risk behaviors of patients with HIV/AIDS over the Course of Antiretroviral Treatment in Northern Vietnam. Int J Environ Res Public Health. 2018;15(6):1106. https://doi.org/10.3390/ijerph15061106. PMID: 29844289; PMCID: PMC6025123.
Google Scholar
Luchters S, Sarna A, Geibel S, Chersich MF, Munyao P, Kaai S, Mandaliya KN, Shikely KS, Rutenberg N, Temmerman M. Safer sexual behaviors after 12 months of antiretroviral treatment in Mombasa, Kenya: a prospective cohort. AIDS Patient Care STDS. 2008;22(7):587–94. https://doi.org/10.1089/apc.2007.0247. PMID: 18601582.
Google Scholar
Jean K, Gagillard D, Moh R, et al. Decrease in sexual risk behaviours after early initiation of antiretroviral therapy: a 24-month prospective study in Côte d’Ivoire. J Int AIDS Soc. 2014;17:18977. https://doi.org/10.7448/IAS.17.1.18977.
Google Scholar
Hasse B, Ledergerber B, Hirschel B, Vernazza P, Glass TR, Jeannin A, Evison JM, Elzi L, Cavassini M, Bernasconi E, Nicca D, Weber R, Swiss HIV. Cohort study. Frequency and determinants of unprotected sex among HIV-infected persons: the Swiss HIV cohort study. Clin Infect Dis. 2010;51(11):1314–22. https://doi.org/10.1086/656809. Epub 2010 Oct 29. PMID: 21034200.
Google Scholar
Dukers NH, Goudsmit J, de Wit JB, Prins M, Weverling GJ, Coutinho RA. Sexual risk behaviour relates to the virological and immunological improvements during highly active antiretroviral therapy in HIV-1 infection. AIDS. 2001;15(3):369–78. https://doi.org/10.1097/00002030-200102160-00010. PMID: 11273217.
Google Scholar
