Congenital disorders

My Bantu vision of genomic medicine in Africa

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The preparedness of Africa for genomic medicine remains a matter of debate because this question is always evaluated from a technological standpoint. Yet the resilience of African researchers and the cultural values of equity and fairness are important assets to be considered in planning for the future of genomic medicine in Africa.

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References

  1. Lumaka, A. et al. Eur. J. Pediatr. 171, 267–270 (2012).

    Article 
    PubMed 

    Google Scholar 

  2. Lumaka, A. et al. Int. J. Mol. Sci. 24, (2023).

  3. H3Africa Consortium. et al. Science 344, 1346–13468 (2014).

    Article 

    Google Scholar 

  4. Lumaka, A. et al. Orphanet J. Rare Dis. 17, 230 (2022).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  5. Sciascia, S. et al. Front. Public Health https://doi.org/10.3389/fpubh.2023.1079601 (2023).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

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Authors and Affiliations

  1. Service de Génétique Humaine, Université de Liège Sart Tilman, Liège, Belgium

    Aimé Lumaka

  2. Centre de Référence des Maladies Rares et Non-diagnostiquées, Centre de Génétique Humaine de l’Université de Kinshasa, Faculté de Médecine, Université de Kinshasa, Kinshasa, Democratic Republic of the Congo

    Aimé Lumaka

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  1. Aimé Lumaka
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Aimé Lumaka.

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Lumaka, A. My Bantu vision of genomic medicine in Africa.
Nat Genet (2023). https://doi.org/10.1038/s41588-023-01566-w

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  • Published: 13 November 2023

  • DOI: https://doi.org/10.1038/s41588-023-01566-w

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