ADHD medications and long-term risk of cardiovascular diseases

About The Study: Longer cumulative duration of attention-deficit/hyperactivity disorder (ADHD) medication use was associated with an increased risk of cardiovascular disease, particularly hypertension and arterial disease, compared with nonuse in this study of 278,000 individuals in Sweden ages 6 to 64 who had an incident ADHD diagnosis or ADHD medication dispensation. These findings highlight the importance of carefully weighing potential benefits and risks when making treatment decisions about long-term ADHD medication use. Clinicians should regularly and consistently monitor cardiovascular signs and symptoms throughout the course of treatment. 

Authors: Zheng Chang, Ph.D., and Le Zhang, Ph.D., of the Karolinska Institutet in Stockholm, are the corresponding authors.

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(10.1001/jamapsychiatry.2023.4294)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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