Prognostic value of triglyceride-glucose index in patients with chronic coronary syndrome undergoing percutaneous coronary intervention

  • Tsao CW, Aday AW, Almarzooq ZI, Alonso A, Beaton AZ, Bittencourt MS, et al. Heart Disease and Stroke statistics-2022 update: a report from the American Heart Association. Circulation. 2022;145(8):e153–e639. https://doi.org/10.1161/CIR.0000000000001052. Epub 2022 Jan 26. Erratum in: Circulation. 2022;145(8):e153-e639. doi:10.1161/CIR.0000000000001052.

    Article 
    PubMed 

    Google Scholar 

  • GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 Diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the global burden of Disease Study 2019. Lancet. 2020;396(10258):1204–22. https://doi.org/10.1016/S0140-6736(20)30925-9.

    Article 

    Google Scholar 

  • Knuuti J, Wijns W, Saraste A, Capodanno D, Barbato E, Funck-Brentano C, et al. 2019 ESC guidelines for the diagnosis and management of chronic coronary syndromes. Eur Heart J. 2020;41(3):407–77. https://doi.org/10.1093/eurheartj/ehz425.

    Article 
    PubMed 

    Google Scholar 

  • Virani SS, Newby LK, Arnold SV, Bittner V, Brewer LC, Demeter SH, et al. 2023 AHA/ACC/ACCP/ASPC/NLA/PCNA guideline for the management of patients with chronic coronary Disease: a report of the American Heart Association/American College of Cardiology Joint Committee on clinical practice guidelines. Circulation. 2023;148(9):e9–e119. https://doi.org/10.1161/CIR.0000000000001168.

    Article 
    PubMed 

    Google Scholar 

  • Lettieri C, Zavalloni D, Rossini R, Morici N, Ettori F, Leonzi O, et al. Management and long-term prognosis of spontaneous coronary artery dissection. Am J Cardiol. 2015;116(1):66–73. https://doi.org/10.1016/j.amjcard.2015.03.039.

    Article 
    PubMed 

    Google Scholar 

  • Tweet MS, Eleid MF, Best PJ, Lennon RJ, Lerman A, Rihal CS, et al. Spontaneous coronary artery dissection: revascularization versus Conservative therapy. Circ Cardiovasc Interv. 2014;7(6):777–86. https://doi.org/10.1161/CIRCINTERVENTIONS.114.001659.

    Article 
    PubMed 

    Google Scholar 

  • Saw J, Aymong E, Sedlak T, Buller CE, Starovoytov A, Ricci D, et al. Spontaneous coronary artery dissection: association with predisposing arteriopathies and precipitating stressors and cardiovascular outcomes. Circ Cardiovasc Interv. 2014;7(5):645–55. https://doi.org/10.1161/CIRCINTERVENTIONS.114.001760.

    Article 
    PubMed 

    Google Scholar 

  • Lawton JS, Tamis-Holland JE, Bangalore S, Bates ER, Beckie TM, Bischoff JM, et al. 2021 ACC/AHA/SCAI guideline for coronary artery revascularization: a report of the American College of Cardiology/American Heart Association Joint Committee on clinical practice guidelines. Circulation. 2022;145(3):e18–14. https://doi.org/10.1161/CIR.0000000000001038.

    Article 
    PubMed 

    Google Scholar 

  • Tam DY, Dharma C, Rocha R, Farkouh ME, Abdel-Qadir H, Sun LY, et al. Long-term survival after surgical or percutaneous revascularization in patients with Diabetes and multivessel coronary Disease. J Am Coll Cardiol. 2020;76(10):1153–64. https://doi.org/10.1016/j.jacc.2020.06.052.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Parasca CA, Head SJ, Milojevic M, Mack MJ, Serruys PW, Morice MC, et al. Incidence, characteristics, predictors, and outcomes of repeat revascularization after percutaneous coronary intervention and coronary artery bypass grafting: the SYNTAX trial at 5 years. JACC Cardiovasc Interv. 2016;9(24):2493–507. https://doi.org/10.1016/j.jcin.2016.09.044.

    Article 
    PubMed 

    Google Scholar 

  • Huang R, Wang Z, Chen J, Bao X, Xu N, Guo S, et al. Prognostic value of triglyceride glucose (TyG) index in patients with acute decompensated Heart Failure. Cardiovasc Diabetol. 2022;21(1):88. https://doi.org/10.1186/s12933-022-01507-7.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Di Pino A, DeFronzo RA. Insulin resistance and Atherosclerosis: implications for insulin-sensitizing agents. Endocr Rev. 2019;40(6):1447–67. https://doi.org/10.1210/er.2018-00141.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Louie JZ, Shiffman D, McPhaul MJ, Melander O. Insulin resistance probability score and incident Cardiovascular Disease. J Intern Med. 2023;294(4):531–5. https://doi.org/10.1111/joim.13687.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Echouffo-Tcheugui JB, Zhang S, McEvoy JW, Juraschek SP, Fang M, Ndumele CE, et al. Insulin resistance and N-Terminal Pro-B-Type Natriuretic peptide among healthy adults. JAMA Cardiol. 2023;8(10):989–95. https://doi.org/10.1001/jamacardio.2023.2758.

    Article 
    PubMed 

    Google Scholar 

  • Lee JH, Jeon S, Joung B, Lee HS, Kwon YJ. Associations of homeostatic model assessment for insulin resistance trajectories with Cardiovascular Disease incidence and mortality. Arterioscler Thromb Vasc Biol. 2023;43(9):1719–28. https://doi.org/10.1161/ATVBAHA.123.319200.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Guerrero-Romero F, Villalobos-Molina R, Jiménez-Flores JR, Simental-Mendia LE, Méndez-Cruz R, Murguía-Romero M, et al. Fasting triglycerides and glucose index as a diagnostic test for insulin resistance in young adults. Arch Med Res. 2016;47(5):382–7. https://doi.org/10.1016/j.arcmed.2016.08.012.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Guerrero-Romero F, Simental-Mendía LE, González-Ortiz M, Martínez-Abundis E, Ramos-Zavala MG, Hernández-González SO, et al. The product of triglycerides and glucose, a simple measure of insulin sensitivity. Comparison with the euglycemic-hyperinsulinemic clamp. J Clin Endocrinol Metab. 2010;95(7):3347–51. https://doi.org/10.1210/jc.2010-0288.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Brito ADM, Hermsdorff HHM, Filgueiras MS, Suhett LG, Vieira-Ribeiro SA, Franceschini SDCC, et al. Predictive capacity of triglyceride-glucose (TyG) index for insulin resistance and cardiometabolic risk in children and adolescents: a systematic review. Crit Rev Food Sci Nutr. 2021;61(16):2783–92. https://doi.org/10.1080/10408398.2020.1788501.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Barzegar N, Tohidi M, Hasheminia M, Azizi F, Hadaegh F. The impact of triglyceride-glucose index on incident cardiovascular events during 16 years of follow-up: Tehran lipid and glucose study. Cardiovasc Diabetol. 2020;19(1):155. https://doi.org/10.1186/s12933-020-01121-5.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Ma X, Dong L, Shao Q, Cheng Y, Lv S, Sun Y, et al. Triglyceride glucose index for predicting cardiovascular outcomes after percutaneous coronary intervention in patients with type 2 Diabetes Mellitus and acute coronary syndrome. Cardiovasc Diabetol. 2020;19(1):31. https://doi.org/10.1186/s12933-020-01006-7.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Luo E, Wang D, Yan G, Qiao Y, Liu B, Hou J, et al. High triglyceride-glucose index is associated with poor prognosis in patients with acute ST-elevation Myocardial Infarction after percutaneous coronary intervention. Cardiovasc Diabetol. 2019;18(1):150. https://doi.org/10.1186/s12933-019-0957-3.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Degenhardt F, Seifert S, Szymczak S. Evaluation of variable selection methods for random forests and omics data sets. Brief Bioinform. 2019;20(2):492–503. https://doi.org/10.1093/bib/bbx124.

    Article 
    PubMed 

    Google Scholar 

  • Robinson MR, Scheuermann-Freestone M, Leeson P, Channon KM, Clarke K, Neubauer S, et al. Uncomplicated obesity is associated with abnormal aortic function assessed by cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2008;10(1):10. https://doi.org/10.1186/1532-429X-10-10.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Vlachopoulos C, Dima I, Aznaouridis K, et al. Acute systemic inflammation increases arterial stiffness and decreases wave reflections in healthy individuals. Circulation. 2005;112(14):2193–200. https://doi.org/10.1161/CIRCULATIONAHA.105.535435.

    Article 
    PubMed 

    Google Scholar 

  • Perticone M, Maio R, Gigliotti S, Shehaj E, Toscani AF, Capomolla A, et al. Mutual effect modification between insulin resistance and endothelial dysfunction in predicting incident Heart Failure in hypertensives. Biomedicines. 2023;11(8):2188. https://doi.org/10.3390/biomedicines11082188.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Jelenik T, Flögel U, Álvarez-Hernández E, Scheiber D, Zweck E, Ding Z, Rothe M, et al. Insulin resistance and vulnerability to cardiac ischemia. Diabetes. 2018;67(12):2695–702. https://doi.org/10.2337/db18-0449.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Laakso M, Kuusisto J. Insulin resistance and hyperglycaemia in Cardiovascular Disease development. Nat Rev Endocrinol. 2014;10(5):293–302. https://doi.org/10.1038/nrendo.2014.29.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Muniyappa R, Lee S, Chen H, Quon MJ. Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage. Am J Physiol Endocrinol Metab. 2008;294(1):E15–E26. https://doi.org/10.1152/ajpendo.00645.2007.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Unger G, Benozzi SF, Perruzza F, Pennacchiotti GL. Triglycerides and glucose index: a useful indicator of insulin resistance. Endocrinol Nutr. 2014;61(10):533–40. https://doi.org/10.1016/j.endonu.2014.06.009.

    Article 
    PubMed 

    Google Scholar 

  • Mohd Nor NS, Lee S, Bacha F, Tfayli H, Arslanian S. Triglyceride glucose index as a surrogate measure of insulin sensitivity in obese adolescents with normoglycemia, prediabetes, and type 2 Diabetes Mellitus: comparison with the hyperinsulinemic-euglycemic clamp. Pediatr Diabetes. 2016;17(6):458–65. https://doi.org/10.1111/pedi.12303.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Liu X, Tan Z, Huang Y, Zhao H, Liu M, Yu P, et al. Relationship between the triglyceride-glucose index and risk of Cardiovascular Diseases and mortality in the general population: a systematic review and meta-analysis. Cardiovasc Diabetol. 2022;21(1):124. https://doi.org/10.1186/s12933-022-01546-0.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Zheng R, Mao Y. Triglyceride and glucose (TyG) index as a predictor of incident Hypertension: a 9-year longitudinal population-based study. Lipids Health Dis. 2017;16(1):175. https://doi.org/10.1186/s12944-017-0562-y.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Wu Z, Cheng C, Sun X, Wang J, Guo D, Chen S, et al. The synergistic effect of the triglyceride-glucose index and serum uric acid on the prediction of major adverse cardiovascular events after coronary artery bypass grafting: a multicenter retrospective cohort study. Cardiovasc Diabetol. 2023;22(1):103. https://doi.org/10.1186/s12933-023-01838-z.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Thai PV, Tien HA, Van Minh H, Valensi P. Triglyceride glucose index for the detection of asymptomatic coronary artery stenosis in patients with type 2 Diabetes. Cardiovasc Diabetol. 2020;19(1):137. https://doi.org/10.1186/s12933-020-01108-2.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Huang R, Xu X, Xu C, Zhang S, Xiong Z, Liu M, et al. Association between the insulin resistance and all-cause mortality in patients with moderate and severe aortic stenosis: a retrospective cohort study. Cardiovasc Diabetol. 2023;22(1):238. https://doi.org/10.1186/s12933-023-01975-5.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Irace I, Carallo C, Scavelli C, De Franceschi FB, Esposito MS, Tripolino T. Markers of insulin resistance and carotid Atherosclerosis. A comparison of the homeostasis model assessment and triglyceride glucose index. Int J Clin Pract. 2013;67(7):665–72. https://doi.org/10.1111/ijcp.12124.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Vasques AC, Novaes FS, de Oliveira Mda S, Souza JR, Yamanaka A, Pareja JC, et al. TyG index performs better than HOMA in a Brazilian population: a hyperglycemic clamp validated study. Diabetes Res Clin Pract. 2011;93(3):e98–e100. https://doi.org/10.1016/j.diabres.2011.05.030.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Yu X, Wang L, Zhang W, Ming J, Jia A, Xu S, et al. Fasting triglycerides and glucose index is more suitable for the identification of metabolically unhealthy individuals in the Chinese adult population: a nationwide study. J Diabetes Investig. 2019;10(4):1050–8. https://doi.org/10.1111/jdi.12975.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Sánchez-Íñigo L, Navarro-González D, Fernández-Montero A, Pastrana-Delgado J, Martínez JA. The TyG index may predict the development of cardiovascular events. Eur J Clin Invest. 2016;46(2):189–97. https://doi.org/10.1111/eci.12583.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Li S, Guo B, Chen H, Shi Z, Li Y, Tian Q, et al. The role of the triglyceride (triacylglycerol) glucose index in the development of cardiovascular events: a retrospective cohort analysis. Sci Rep. 2019;9(1):7320. https://doi.org/10.1038/s41598-019-43776-5.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Jafari A, Najafipour H, Shadkam M, Aminizadeh S. Evaluation of the novel three lipid indices for predicting five- and ten-year incidence of Cardiovascular Disease: findings from Kerman coronary artery Disease risk factors study (KERCADRS). Lipids Health Dis. 2023;22(1):169. https://doi.org/10.1186/s12944-023-01932-x.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Lertsakulbunlue S, Mungthin M, Rangsin R, Kantiwong A, Sakboonyarat B. Trends in baseline triglyceride-glucose index and association with predicted 10-year Cardiovascular Disease risk among type 2 Diabetes patients in Thailand. Sci Rep. 2023;13(1):12960. https://doi.org/10.1038/s41598-023-40299-y.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Liu L, Wu Z, Zhuang Y, Zhang Y, Cui H, Lu F, et al. Association of triglyceride-glucose index and traditional risk factors with Cardiovascular Disease among non-diabetic population: a 10-year prospective cohort study. Cardiovasc Diabetol. 2022;21(1):256. https://doi.org/10.1186/s12933-022-01694-3.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Lee SB, Ahn CW, Lee BK, Kang S, Nam JS, You JH, et al. Association between triglyceride glucose index and arterial stiffness in Korean adults. Cardiovasc Diabetol. 2018;17(1):41. https://doi.org/10.1186/s12933-018-0692-1.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Kim MK, Ahn CW, Kang S, Nam JS, Kim KR, Park JS. Relationship between the triglyceride glucose index and coronary artery calcification in Korean adults. Cardiovasc Diabetol. 2017;16(1):108. https://doi.org/10.1186/s12933-017-0589-4.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Hu C, Zhang J, Liu J, Liu Y, Gao A, Zhu Y, et al. Discordance between the triglyceride glucose index and fasting plasma glucose or HbA1C in patients with acute coronary syndrome undergoing percutaneous coronary intervention predicts cardiovascular events: a cohort study from China. Cardiovasc Diabetol. 2020;19(1):116. https://doi.org/10.1186/s12933-020-01091-8.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Shao QY, Ma XT, Yang ZQ, Li QX, Wang YF, Liang J, et al. Prognostic significance of multiple triglycerides-derived metabolic indices in patients with acute coronary syndrome. J Geriatr Cardiol. 2022;19(6):456–68. https://doi.org/10.11909/j.issn.1671-5411.2022.06.001.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Wan GX, Xia WB, Ji LH, Qin HL, Zhang YG. Triglyceride to high density lipoprotein cholesterol ratio may serve as a useful predictor of major adverse coronary event in female revascularized ST-elevation Myocardial Infarction. Clin Chim Acta. 2018;485:166–72. https://doi.org/10.1016/j.cca.2018.06.049.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Askin L, Tanrıverdi O. Is the atherogenic index of plasma (AIP) a Cardiovascular Disease marker? Cor et Vasa. 2023;65(1):100–3. https://doi.org/10.33678/cor.2022.085.

    Article 

    Google Scholar 

  • Liu Q, Cui H, Ma Y, Han X, Cao Z, Wu Y. Triglyceride-glucose index associated with the risk of Cardiovascular Disease: the Kailuan study. Endocrine. 2022;75(2):392–9. https://doi.org/10.1007/s12020-021-02862-3.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Palmerini T, Della Riva D, Biondi-Zoccai G, et al. Mortality following nonemergent, uncomplicated target lesion revascularization after percutaneous coronary intervention: an individual patient data pooled analysis of 21 randomized trials and 32,524 patients. JACC Cardiovasc Interv. 2018;11(9):892–902. https://doi.org/10.1016/j.jcin.2018.01.277.

    Article 
    PubMed 

    Google Scholar 

  • Zhao Q, Zhang TY, Cheng YJ, Ma Y, Xu YK, Yang JQ, et al. Impacts of triglyceride-glucose index on prognosis of patients with type 2 Diabetes Mellitus and non-ST-segment elevation acute coronary syndrome: results from an observational cohort study in China. Cardiovasc Diabetol. 2020;19(1):108. https://doi.org/10.1186/s12933-020-01086-5.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Mao Q, Zhou D, Li Y, Wang Y, Xu SC, Zhao XH. The triglyceride-glucose index predicts coronary artery Disease severity and cardiovascular outcomes in patients with non-ST-segment elevation acute coronary syndrome. Dis Markers. 2019;2019:6891537. https://doi.org/10.1155/2019/6891537.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Moussa ID, Mohananey D, Saucedo J, Stone GW, Yeh RW, Kennedy KF, et al. Trends and outcomes of restenosis after coronary stent implantation in the United States. J Am Coll Cardiol. 2020;76(13):1521–31. https://doi.org/10.1016/j.jacc.2020.08.002.

    Article 
    PubMed 

    Google Scholar 

  • Assali AR, Moustapha A, Sdringola S, Denktas AE, Willerson JT, Holmes DR Jr, et al. Acute coronary syndrome may occur with in-stent restenosis and is associated with adverse outcomes (the PRESTO trial). Am J Cardiol. 2006;98(6):729–33. https://doi.org/10.1016/j.amjcard.2006.04.007.

    Article 
    PubMed 

    Google Scholar 

  • Zhu Y, Liu K, Chen M, Liu Y, Gao A, Hu C, et al. Triglyceride-glucose index is associated with in-stent restenosis in patients with acute coronary syndrome after percutaneous coronary intervention with drug-eluting stents. Cardiovasc Diabetol. 2021;20(1):137. https://doi.org/10.1186/s12933-021-01332-4.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Özbiçer S, Yüksel G, Deniz Urgun Ö. Triglyceride glucose index is independently associated with aortic intima-media thickness in patients without known atherosclerotic Cardiovascular Disease or Diabetes. Diab Vasc Dis Res. 2022;19(5):14791641221136203. https://doi.org/10.1177/14791641221136203.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Cetin Sanlialp S, Sanlialp M, Nar G, Malcok A. Triglyceride glucose index reflects the unfavorable changes of left ventricular diastolic functions and structure in uncomplicated newly diagnosed hypertensive patients. Clin Exp Hypertens. 2022;44(3):215–22. https://doi.org/10.1080/10641963.2021.2018599.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Wang C, Zhao Z, Deng X, Cai Z, Gu T, Li L, et al. Association of triglyceride-glucose with cardiac hemodynamics in type 2 Diabetes. Diab Vasc Dis Res. 2022;19(1):14791641221083396. https://doi.org/10.1177/14791641221083396.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Gao JW, Hao QY, Gao M, Zhang K, Li XZ, Wang JF, et al. Triglyceride-glucose index in the development of peripheral artery Disease: findings from the Atherosclerosis risk in communities (ARIC) Study. Cardiovasc Diabetol. 2021;20(1):126. https://doi.org/10.1186/s12933-021-01319-1.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

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