Monthly Archives: November 2023

Obesity drug Wegovy reduces cardiovascular risks for those at high risk

Enlarge / Wegovy an injectable prescription weight loss medicine that has helped people with obesity. Getty | Michael Siluk The blockbuster diabetes and weight loss drug semaglutide (Wegovy, Ozempic, Rybelsus) reduced the relative risk of heart attack, stroke, or cardiovascular deaths by 20 percent in high-risk patients with cardiovascular disease but not diabetes during a […]

In-Ear Wearable Measures Blood Flow to the Head for Long COVID POTS

What You Should Know:  STAT Health emerges from stealth to introduce a 24/7 in-ear wearable that measures blood flow to the head to better understand symptoms such as dizziness, brain fog, headaches, fainting, and fatigue that occur upon standing. These are common symptoms for illnesses like long COVID, postural orthostatic tachycardia syndrome (POTS), myalgic encephalomyelitis / […]

Novel siRNA therapeutic could lower cardiovascular disease risk

A Phase II trial for the small interfering RNA (siRNA) therapeutic lepodisiran is currently underway, assessing its ability to reduce lipoprotein(a) levels. A single dose of lepodisiran, a small interfering RNA (siRNA) therapeutic, produced over 94 percent reductions in blood levels of lipoprotein(a), also known as Lp(a), with the results lasting for nearly a year, […]

Blood thinner apixaban found to prevent strokes in patients with device-detected atrial fibrillation

A 12 lead ECG showing atrial fibrillation at approximately 150 beats per minute. Credit: James Heilman, MD/Wikipedia/CC BY-SA 3.0 The widely available blood thinner apixaban substantially reduced stroke in at-risk patients with a type of atrial fibrillation only detectable by a pacemaker or other implanted cardiac electronic device, a global study has found. The oral […]

New VP&S Faculty

The VP&S Office of Faculty Affairs has provided this list of full-time faculty who joined the medical school in August 2023.  Amit Batta, DO, Psychiatry Jehanne Belange, MD, Emergency Medicine Tom D. Ben Dov, MD, Otolaryngology/Head & Neck Surgery: Ben Dov has joined the Division of Pediatric Otolaryngology. His research interests focus on the genomics […]

Novo Nordisk says Wegovy can help heart disease patients—and not just because it produces weight loss

Novo Nordisk has made a splash with its GLP-1 drugs that have allowed patients to achieve significant weight loss. Now the Danish company appears on the verge of another breakthrough, showing that the use of its obesity treatment Wegovy can reduce the risk of heart attack in some patients. Perhaps even more importantly, Novo said […]

Adzynma Approved for Congenital Thrombotic Thrombocytopenic Purpura

The Food and Drug Administration (FDA) has approved Adzynma for prophylactic or on-demand enzyme replacement therapy (ERT) in adult and pediatric patients with congenital thrombotic thrombocytopenic purpura. Congenital thrombotic thrombocytopenic purpura (cTTP) results from a deficiency in  ADAMTS13 (A disintegrin and metalloproteinase with thrombospondin motifs 13), a von Willebrand factor (VWF) cleaving protease. This leads […]

Wegovy weight loss drug has heart health benefits, study found

(CNN) – Results from a landmark clinical trial this summer suggested, for the first time, that a medication given for weight loss alone could reduce the risk of heart attack, stroke or heart-related death in people with cardiovascular disease, bolstering physicians’ excitement about an already-exploding class of new medicines. Novo Nordisk’s Wegovy, part of the […]

SELECT Trial Data On Weight Loss Drug Wegovy May Not Be Enough To Convince Payers

Data presented at a meeting of the American Heart Association on Saturday indicates cardiovascular protective benefits from taking the weight loss therapeutic Wegovy for a sub-population with preexisting cardiovascular disease. But the absolute risk reduction is quite small. Payers will take notice of this in addition to the timing aspect with respect to when the […]