Monthly Archives: November 2023

Mendelian Randomization as a Tool for Cardiovascular Research

Importance  Mendelian randomization (MR) is a statistical approach that has become increasingly popular in the field of cardiovascular disease research. It offers a way to infer potentially causal relationships between risk factors and outcomes using observational data, which is particularly important in cases where randomized clinical trials are not feasible or ethical. With the growing […]

Chicago’s Mpox Outbreak Included Other Sexually Transmitted Infections

(Precision Vaccinations News) A study led by Chicago Department of Public Health researchers published in the Journal of Infectious Diseases involved estimating rates of HIV, gonorrhea, and chlamydia among mpox patients. This study was published on November 8, 2023, and identified factors related to mpox severity from June 2022 to March 2023. These researchers concluded that sexually transmitted infections (STIs) […]

Perspectives and Strategies to Minimize Harm From Melanoma Diagnosis

Kerr et al1 report a study of pathologists who reviewed slides of melanocytic nevi and melanomas. The pathologists were asked to grade the atypia of lesions as low vs high and to distinguish them from invasive melanoma. Seeking to identify pathologist characteristics associated with tumor categorization, the authors found that dermatopathologists were more likely than […]

Syphilis cases surge in pregnant women and infants in Illinois

Public health experts are warning about an “alarming” increase in congenital syphilis cases across the state and the impact on pregnant women and infants. Cases of infants contracting syphilis from their mothers almost tripled in two years, the Illinois Department of Public Health reported, from 29 infections in 2020 to 50 in 2021 and 84 […]

Asymptomatic and submicroscopic malaria infections in sugar cane and rice development areas of Ethiopia

Lipton M, Litchfield J, Faurès JM. The effects of irrigation on poverty: a framework for analysis. Water Policy. 2003;5:413–27. Article  Google Scholar  Hawaria D, Demissew A, Kibret S, Lee M, Yewhalaw D. Effects of environmental modification on the diversity and positivity of anopheline mosquito aquatic habitats at Arjo-Dedessa irrigation development site Southwest Ethiopia. Infect Dis […]

What Is Cardiovascular-Kidney-Metabolic Syndrome?

Cardiovascular disease often occurs with kidney disease and metabolic diseases, including obesity and type 2 diabetes. And having more than 1 of these conditions multiplies health and mortality risks, particularly due to cardiovascular disease. An American Heart Association (AHA) presidential advisory recently published in Circulation newly defines the adverse interplay among these conditions as cardiovascular-kidney-metabolic […]

Microglia are not protective against cryptococcal meningitis

Abstract Microglia provide protection against a range of brain infections including bacteria, viruses and parasites, but how these glial cells respond to fungal brain infections is poorly understood. We investigated the role of microglia in the context of cryptococcal meningitis, the most common cause of fungal meningitis in humans. Using a series of transgenic- and […]