15 Possible Causes of Brain Fogginess

Many of us have experienced the phenomenon known as “brain fog,” which refers to a feeling of mental cloudiness, difficulty focusing, fatigue, forgetfulness, or making errors. However, the severity of brain fog can vary, and for some individuals, it can be a persistent and debilitating part of their daily life.

Brain fog can be associated with factors such as stress, inadequate sleep, or excessive physical or mental exertion. In these cases, making lifestyle adjustments, such as managing stress, improving sleep habits, and taking breaks when needed, may help alleviate symptoms. However, if brain fog persists, significantly interferes with your daily functioning, or has a negative impact on your mental well-being, it is advisable to consult with a healthcare provider. There could be an underlying cause contributing to your symptoms that requires medical attention and appropriate treatment.

It is important to recognize that brain fog is not a normal state and should not be ignored if it is significantly impacting your quality of life. Seeking professional guidance can help identify any underlying issues and guide you towards appropriate interventions to address and manage brain fog effectively.

1. Lyme Disease

Lyme disease, which is transmitted through the bite of an infected tick, can give rise to various symptoms, including brain fog. The initial manifestation of the disease often involves the appearance of a distinctive “bulls-eye” rash. As the infection progresses, individuals may experience mental fogginess or difficulty with cognitive functions.

Brain fog associated with Lyme disease can occur at any time following the infection and may manifest as challenges in engaging in conversations, retaining information, or experiencing difficulty in finding the right words.

If you are experiencing brain fog and have a history of tick bite, it is crucial to seek medical assistance promptly. Similarly, if you notice the presence of a bulls-eye rash, medical attention should be sought immediately. Early diagnosis and treatment, typically involving the administration of antibiotics, can lead to successful recovery for most individuals.

2. Lupus

Lupus is a chronic autoimmune disease characterized by the immune system mistakenly attacking the body’s healthy cells, resulting in inflammation and pain. The exact cause of systemic lupus erythematosus (SLE), the most common form of lupus, is unknown. According to the CDC, SLE affects approximately 200,000 adults in the United States.

Within the lupus community, “lupus fog” is a term used to describe the cognitive symptoms experienced by individuals with lupus. This brain fog can manifest as memory lapses, difficulty concentrating, and confusion. People with lupus-related brain fog may struggle with familiar tasks, recalling names, maintaining a schedule, and processing thoughts.

For some individuals, these symptoms can significantly interfere with daily life. It’s important to discuss your symptoms with a healthcare provider who can provide appropriate lupus treatments to address your specific needs and offer strategies to cope with memory issues.

The National Resource Center on Lupus suggests engaging in activities such as reading books, doing puzzles, and using planners or color-coded calendars as ways to manage lupus-related brain fog. These activities can help improve cognitive function and organization skills.

3. Multiple Sclerosis

Multiple sclerosis (MS) is a chronic inflammatory disease that can lead to the development of lesions on the central nervous system, affecting various aspects such as motor function, emotions, cognition, and clarity of thinking. Individuals with MS often refer to their experience of brain fog as “cog fog,” which stands for “cognitive fog.”

Cognitive fog in MS typically impacts information processing speed and memory recall. Individuals may struggle with tasks that require quick thinking or remembering information. Finding the right words, remembering how to perform certain tasks, and making decisions can be challenging.

Research has also shown a connection between multiple sclerosis and sleep disorders, indicating that lack of sleep or restless sleep can worsen brain fog symptoms.

During MS flares, brain fog may become more pronounced, and environmental factors such as heat can exacerbate the symptoms. For example, brain fog may worsen on hot days, in hot rooms, or when a person has a fever.

It is important to address brain fog symptoms with a healthcare provider to explore potential medication options and rule out other factors like depression or medications for other symptoms that may contribute to cognitive difficulties. Developing strategies to work around brain fog can also be helpful, such as tackling mentally challenging tasks earlier in the day if brain fog tends to worsen later in the day.

4. Chronic Fatigue Syndrome (CFS)

Chronic fatigue syndrome (CFS), also known as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), is characterized by persistent physical and cognitive fatigue lasting more than six months. Rest does not alleviate the fatigue, and it is not necessarily triggered by exertion. In addition to physical fatigue, individuals with CFS often experience brain fog, which is described as sluggish or hazy thinking, difficulty focusing and concentrating, and forgetfulness.

The exact cause of CFS is still unknown, but research suggests that neuroinflammation may play a role. A study published in the Journal of Nuclear Medicine in 2014 found evidence of “widespread” neuroinflammation in individuals with CFS, highlighting the potential importance of this factor in developing diagnostic criteria and treatment approaches.

People with CFS often face stigma and disbelief, which can be challenging and exacerbate the impact of their symptoms. The brain fog associated with CFS may interfere with work and social activities, leading to frustration, anxiety, and depression.

It is important for individuals with CFS to seek understanding and support from healthcare providers and to connect with others who have similar experiences. Managing symptoms and finding coping strategies, both for physical fatigue and cognitive difficulties like brain fog, can be an ongoing process that requires a multidisciplinary approach and support from a healthcare team.

5. Celiac Disease

Celiac disease is an example of a condition that primarily affects the gut but can manifest with symptoms throughout the body.

In individuals with celiac disease, the consumption of gluten triggers an immune response that leads to inflammation and damage to the small intestine. This results in various gastrointestinal symptoms such as abdominal pain, bloating, diarrhea, and constipation, as outlined by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). However, celiac disease can also cause symptoms beyond the gut, including fatigue, joint pain, and mouth sores. Some of these symptoms may even affect the brain.

People with celiac-related brain fog often describe feelings of disorientation, difficulty concentrating or paying attention, and forgetfulness. A study published in July 2014 in Alimentary Pharmacology and Therapeutics showed that individuals with celiac disease who strictly adhered to a gluten-free diet experienced improvements in cognitive performance.

Managing celiac disease involves following a gluten-free diet, which entails avoiding foods containing wheat, barley, rye, and other gluten-containing grains. This dietary approach is crucial not only for gut health but also for addressing associated symptoms, including brain fog.

6. Migraines

Migraines are known for their severe and debilitating nature, encompassing symptoms such as intense head pain, nausea, vomiting, and fatigue. These symptoms can contribute to a foggy sensation in the brain.

According to the American Migraine Foundation, brain fog can occur up to 48 hours before and 24 hours after a migraine attack. Following a migraine, individuals may experience what is commonly referred to as a “migraine hangover” or “postdrome,” during which brain fog is a common feature. It is not uncommon for the brain to feel unclear or clouded during this period.

A study published in July 2016 in the journal Neurology examined the symptoms of postdrome and revealed that patients commonly reported feelings of fatigue, difficulty concentrating, and a stiff neck.

7. Underactive Thyroid

The thyroid hormone plays a crucial role in regulating the body’s energy levels. When the thyroid function is impaired, it can have widespread effects on the body. Hypothyroidism, an underactive thyroid, can lead to symptoms such as weight gain, sluggishness, and depression, as noted by the NIDDK.

Brain fog associated with thyroid dysfunction manifests as difficulty concentrating, memory problems, absentmindedness, and confusion. It’s important to note that hypothyroidism often progresses slowly, and the onset of brain fog may be subtle, initially mistaken for a temporary mental fog.

A survey published in March 2022 in the journal Endocrine Practice found that individuals with hypothyroidism who experienced brain fog primarily associated it with fatigue and forgetfulness. Brain fog can significantly disrupt daily life and have a negative impact on overall well-being. A review published in May 2022 in the journal Thyroid highlighted that brain fog in individuals with hypothyroidism resulted in distress and a reduced quality of life.

8. Menopause

Menopause, the stage when a person’s menstrual cycle permanently ceases, typically occurs in their 40s or 50s. While hot flashes and mood swings are well-known symptoms of menopause, brain fog is a lesser-known but significant symptom.

A review published in July 2016 in the journal Menopause highlighted that women experiencing menopause reported feelings of forgetfulness and difficulty concentrating. Additionally, a study published in 2013 in Menopause found that women in the early stages of menopause experienced more cognitive issues, particularly in verbal learning and memory, motor function, and attention, compared to women in later menopausal stages. This suggests that brain fog may be more prevalent during the initial phase of menopause.

9. Pregnancy

memory difficulties that pregnant individuals may experience during pregnancy.

The impact of pregnancy on cognitive abilities is still not fully understood and requires further research. However, a study published in May 2014 in the Journal of Clinical and Experimental Neuropsychology found that pregnant and postpartum individuals more commonly self-reported memory difficulties.

Pregnancy can also have an effect on sleep quality. Discomfort, frequent urination, back pain, heartburn, leg cramps, and anxiety are common experiences during pregnancy that can make it challenging to get a good night’s sleep. This lack of quality sleep can contribute to feelings of tiredness and brain fog. It is advisable to discuss any sleep concerns with your healthcare provider, who can provide guidance and suggestions to help improve your sleep quality during pregnancy.

Each pregnancy is unique, and not all individuals may experience the same degree of brain fog or sleep disruptions. It’s important to communicate any concerns or symptoms you may be experiencing with your healthcare provider, as they can provide personalized advice and support throughout your pregnancy journey.

10. Premenstrual Syndrome (PMS)

Premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) are conditions that can bring about a variety of symptoms, including abdominal and back pain, headaches, nausea, and anxiety. In addition to these symptoms, brain fog is a frustrating experience that some people refer to as “period brain.”

Fluctuations in hormones, such as estrogen and progesterone, which occur throughout the menstrual cycle, appear to have an influence on cognitive function, as noted in a review published in April 2020 in Brain Sciences. The review also highlighted that individuals have reported difficulties with concentration during the late luteal phase, which is the phase that occurs after ovulation and before the onset of menstruation.

11. Depression and Anxiety

Depression is often associated with feelings of sadness and loss of interest, but it can also affect cognitive function, according to the National Institute of Mental Health (NIMH). Individuals with depression may experience slowed thinking and speech, difficulty concentrating, making decisions, and remembering things, as noted in a review published in September 2015 in Annals of General Psychology.

Similarly, anxiety disorders can also contribute to brain fog, as stated in a review published in March 2016 in Psychological Bulletin. Unfortunately, the cognitive effects of depression and anxiety can worsen self-perception and make it challenging to seek help. However, there are various effective medications and therapy options available for treating depression and anxiety, which may also help alleviate cognitive symptoms.

12. Sleep Disorders

Sleep disorders can contribute to more severe and frequent brain fog. If you suspect that you have a sleep disorder, it is important to consult with your healthcare provider to determine if you have an isolated sleeping disorder or if there is an underlying cause that affects your ability to fall or stay asleep.

Common sleep disorders include insomnia (difficulty sleeping), narcolepsy (excessive daytime sleepiness), restless legs syndrome (leg pain or discomfort at night), and sleep apnea (interrupted breathing during sleep). These conditions can significantly impact your quality of sleep and contribute to brain fog.

Sleep deprivation, resulting from these sleep disorders, can have a profound impact on cognitive function. Studies have shown that feeling tired throughout the day can impair attention, decision-making, and task completion. Additionally, sleep deprivation has been linked to the creation of false memories.

13. Sjogren’s Syndrome

Sjogren’s syndrome, a chronic inflammatory autoimmune disease, is commonly associated with symptoms such as dry eyes and dry mouth. However, brain fog can also be experienced by individuals with this condition. Typically, brain fog in Sjogren’s syndrome manifests as memory lapses and difficulties with concentration.

Research indicates that cognitive challenges may even precede an official diagnosis of Sjogren’s syndrome. A systematic review highlighted that in some cases, cognitive dysfunction was the initial clinical manifestation of the disease. The relationship between Sjogren’s syndrome and cognitive dysfunction requires further investigation, as brain fog may be influenced by another common symptom of the condition: fatigue.

14. Fibromyalgia

Fibromyalgia is a chronic disorder characterized by widespread tenderness, musculoskeletal pain, and other symptoms. It predominantly affects women and can take time to be accurately diagnosed since there is no specific test for the condition.

Individuals with fibromyalgia commonly experience brain fog, often referred to as “fibro fog.” This includes symptoms such as forgetfulness, difficulty concentrating, and a general feeling of mental fogginess. Research studies have highlighted the cognitive impairments associated with fibromyalgia, further emphasizing the impact of brain fog on individuals with the condition. Additionally, the pain, sleep disturbances, and increased fatigue associated with fibromyalgia can contribute to the severity of brain fog symptoms.

15. Cirrhosis

Cirrhosis of the liver, typically caused by heavy alcohol use or hepatitis C, is a chronic liver disease that can lead to hepatic encephalopathy (HE), a nervous system disorder with cognitive effects. HE occurs when the liver fails to effectively metabolize ammonia, resulting in its buildup in the body. This excess ammonia can reach the brain and cause symptoms referred to as “brain fog.” While HE can manifest as minor symptoms like irritability, it can also progress to more severe cases, potentially leading to a coma.

For individuals with cirrhosis, it is important to consult with a healthcare provider to establish a suitable treatment plan. Additionally, it is recommended to stop consuming alcohol, as advised by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Proper management of cirrhosis and HE is crucial for the overall well-being and cognitive function of individuals affected by these conditions.