ASXL1 mutation is a novel risk factor for bleeding in Philadelphia-negative myeloproliferative neoplasms

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Fig. 1: Candidate risk factors of bleeding in Philadelphia-negative myeloproliferative neoplasms.
Fig. 2: Associations between ASXL1 mutations and clinical variables in Philadelphia-negative myeloproliferative neoplasms.

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Authors

Contributions

HA and MB collected, analyzed, and interpreted the data, and wrote the manuscript; HY, WJ, and SH studied and analyzed the data and applied biostatistical methods; TR provided patients’ data; SBA, AMR, and MSF provided important editing and wrote the manuscript; PK and JM provided important editing and wrote the manuscript; EAG provided patients and provided important editing and wrote the manuscript; AE conceptualized and designed the study and wrote the manuscript. All authors have read and agreed to the published version of the manuscript.

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Correspondence to
Amro Elshoury.

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EAG discloses conflicts of interest including direct fees for advisory services from: AbbVie, Alexion Pharmaceuticals, Apellis, Celgene/BMS, CTI Biopharma, Genentech, Novartis, Picnic Health, Takeda Oncology, Taiho Oncology, Research Funding to Roswell Park from Astex Pharmaceuticals, AstraZeneca Rare Disease, Alexion Pharmaceuticals, Apellis Pharmaceuticals, Blueprint Medicines, Genentech Inc. and CME/Honoraria payments from Physicians Educational Resource, MediCom Worldwide, American Society of Hematology, AAMDS International Foundation, MDS International Foundation, and the Vera & Joseph Dresner Foundation.

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Awada, H., Bhatta, M., Yu, H. et al. ASXL1 mutation is a novel risk factor for bleeding in Philadelphia-negative myeloproliferative neoplasms.
Leukemia (2023). https://doi.org/10.1038/s41375-023-02069-7

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  • Received: 27 July 2023

  • Revised: 25 September 2023

  • Accepted: 09 October 2023

  • Published: 03 November 2023

  • DOI: https://doi.org/10.1038/s41375-023-02069-7

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