Author Archives: yun

UTIs to Yeast Infections: 5 side effects of wearing a shapewear every day

Image Source : FREEPIK Know the 5 major side effects of wearing shapewear every day. It’s no secret that shapewear is popular among women of all sizes and shapes. From slimming body suits to tummy control panties, many of us are drawn to shapewear as a way to better our appearance and boost our confidence. […]

Potential Need to Update Recommendations for CNS Prophylaxis in ALL

Partow Kebriaei, MD Over the past few decades, research has advanced the therapeutic landscape of acute lymphoblastic leukemia (ALL), especially for adult patients with Philadelphia chromosome (Ph)-positive ALL.1 With the emergence of tyrosine kinase inhibitors and use of targeted immunotherapies in the front line, outcomes for patients with ALL have significantly improved. However, central nervous […]

Current and Emergent Therapies for Systemic Mastocytosis

Systemic mastocytosis (SM) is a hematologic neoplasm characterized by clonal proliferation of mast cells in 1 or more organs including skin, bone marrow, gastrointestinal tract, spleen and/or liver.1 The underlying molecular pathogenesis of SM is an activating mutation in the KIT gene that leads to the constitutive proliferation of mast cells. In nearly 95% of […]

Triplet Regimens Are New Frontier for AML Therapy

Courtney D. DiNardo, MD, MSCE Treatment for acute myelocytic leukemia (AML) has evolved into finding the right approach based on a patient’s risk status and ability to tolerate high-intensity therapies. Triplet therapy regimens now are on the horizon for patients with AML, thanks to ongoing research into targeted therapies. “When we talk about triplets, we’re […]

Menin Inhibitors Show Promising New Approach for KMT2A-Mutated Leukemia

Eytan M. Stein, MD Although new therapies have improved outcomes for many patients with high-risk leukemia, some patients are less responsive to novel therapies and optimized chemotherapy approaches. Patients with acute leukemia with KMT2A rearrangements are a population with a pressing need for better treatment options. “In 2023, the standard regimens for patients with KMT2A […]

Is Fixed-Duration Therapy the New Standard of Care in Frontline Chronic Lymphocytic Leukemia?

chronic lymphocytic leukemia © Dr_Microbe – stock.adobe.com The advent of small molecule inhibitors, both Bruton tyrosine kinase inhibitors (BTKi) and B-cell lymphoma 2 antagonists, has led to a paradigm shift in the treatment of chronic lymphocytic leukemia (CLL). Fixed-duration (FD) therapy is an appealing approach to initial treatment of CLL from a patient’s and a […]

Should Patients With Smoldering Myeloma Be Treated or Observed?

Angela Dispenzieri, MD Due the asymptomatic nature of smoldering multiple myeloma (MM), plenty of conjecture about approaching treatment of the disorder exists. However, with guidelines, as well as observational and prospective data, experts have been able to make research-driven treatment decisions for their patients with smoldering MM. At the 11th Annual Meeting of the Society […]

Research reveals three-fold increase in obesity-related cardiovascular disease deaths between 1999 and 2020

There has been a recent three-fold increase in obesity-related deaths from heart disease in the U.S. between 1999 and 2020, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association. The number of people with obesity is rising in every country […]

CDC Warns About ‘Flesh-Eating’ Bacteria In East Coast Waters—Experts Explain The Risk

Flesh-eating bacteria sounds like something out of a horror movie. But unfortunately, it’s a real thing. And the Centers for Disease Control and Prevention is warning healthcare providers to be on the lookout for it. The CDC’s health alert, which was released late last week, urges doctors to watch for symptoms of vibrio vulnificus bacteria […]

Community-based, self-measured blood pressure control programs helped at-risk patients

Research Highlights: Community health centers participating in the National Hypertension Control Initiative (NHCI) that introduced self-measured blood pressure interventions to their patients — including individuals from Black, Hispanic and American Indian/Alaskan Native populations, who are disproportionately impacted by hypertension and by the COVID-19 pandemic — experienced improvements in blood pressure control rates since 2021, when […]