Category Archives: Cancer and neoplasms

Knowledge Shortfalls Among Parents of Children with Sickle Cell Disease

Substantial shortfalls in knowledge exist among parents of children with sickle cell disease (SCD) related to pneumococcal infection prophylaxis (PIP), according to recent findings, pointing to a need for greater spread of awareness of PIP in clinics for SCD.1 These findings resulted from a recent cross-sectional study looking at the different viewpoints, perceptions, and awareness […]

Low Cholesterol Levels Associated with Greater Risk of Plasma Cell Neoplasm

Credit: Fotolia Results from a prospective cohort study are providing clinicians with an overview of the association between blood serum cholesterol levels and risk of plasma cell neoplasm. Although findings showed decreased serum total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), apolipoprotein A (ApoA), and apolipoprotein B (ApoB) levels were all associated with an increased […]

Enduring questions in regenerative biology and the search for answers

Abstract The potential for basic research to uncover the inner workings of regenerative processes and produce meaningful medical therapies has inspired scientists, clinicians, and patients for hundreds of years. Decades of studies using a handful of highly regenerative model organisms have significantly advanced our knowledge of key cell types and molecular pathways involved in regeneration. […]

Harpoon Therapeutics Reports Third Quarter 2023 Financial Results and Provides Corporate Update

October 2023 financing funds late-stage clinical trials of HPN328 in multiple tumor types Positive interim results from Phase 1/2 trial of T cell engager HPN328 in patients with small cell lung cancer (SCLC) and other neuroendocrine tumor types presented at ESMO 2023 HPN328 Phase 2 monotherapy dose(s) selection on track for year-end 2023 for discussion […]

Severe Asthma Exacerbations: Spotlighting Trends Before and After COVID-19 Restrictions

Credit: Pexels The total number of admissions to a pediatric intensive care unit (PICU) for those with severe asthma exacerbations (SAE) in the Netherlands decreased in the first year of the COVID-19 pandemic, according to new findings, though they increased significantly for SAE in 2021 and 2022 as COVID-19 restrictions lifted.1 The investigators that reported […]

Analysis of PD-1 inhibitors in pancreatic cancer

Zhitao Chen,1,* Yahui He,2,* Chenchen Ding,3 Jun Chen,2 Yangjun Gu,1 Min Xiao,1 Qiyong Li1 1Hepatobiliary and Pancreatic Surgery, Shulan (Hangzhou) Hospital Affiliated to Zhejiang Shuren University Shulan International Medical College, Hangzhou, 310003, People’s Republic of China; 2School of Medicine, Zhejiang Chinese Medical University Zhejiang Shuren College, Hangzhou, 310003, People’s Republic of China; 3Child and Adolescent […]