Category Archives: Cancer and neoplasms

Perspectives and Strategies to Minimize Harm From Melanoma Diagnosis

Kerr et al1 report a study of pathologists who reviewed slides of melanocytic nevi and melanomas. The pathologists were asked to grade the atypia of lesions as low vs high and to distinguish them from invasive melanoma. Seeking to identify pathologist characteristics associated with tumor categorization, the authors found that dermatopathologists were more likely than […]

Preliminary Data from SPARTAN Trial Presented at ASN 2023

Jonathan Barratt, MD Credit: IgA Nephropathy Foundation Preliminary findings from the SPARTAN trial assessing the safety and efficacy of sparsentan showed the treatment was safe and well-tolerated as a first-line therapy in patients with newly diagnosed immunoglobulin A nephropathy (IgAN). Data through 12 weeks of treatment in the open-label, single-arm, multi-center, exploratory trial was presented […]

Kidney Week 2023: Spotlighting Disparities in Nephrology

Credit: Fotolia The need for greater focus on racial disparities in health care and health outcomes has become impossible to ignore across all specialties in medicine in recent years. Among patients with kidney disease, long-standing disparities have contributed to increased prevalence and disease-related mortality. These differences have been the focal point of calls from nephrologists […]

Trastuzumab Deruxtecan Elicits Activity in HER2-Expressing Solid Tumors

Funda Meric-Bernstam, MD New data on fam-trastuzumab deruxtecan-nxki (Enhertu) has maintained clinically meaningful and durable responses in patients with HER2-expressing advanced solid tumors, according to the primary analysis of the ongoing phase 2 DESTINY-PanTumor02 trial (NCT04482309).1 The median progression-free survival was 6.9 months (95% CI, 5.6-8.0) and the median overall survival was 13.4 months (95% […]

Abandoned oil mess still plagues communities in the Ecuadorian Amazon

The environmental damage caused more than half a century of oil activity in Ecuador’s Amazon are multiplying yearly without effective remediation by the government or the oil companies responsible. To date, there are 1,107 recorded “environmental liabilities” and another 3,568 sites in the Ecuadorian Amazon labeled by the environment ministry as “sources of contamination.” Although […]