Category Archives: Cancer and neoplasms

iOnctura to present research on roginolisib and IOA-359 at ASH

Three abstracts accepted by ASH with two poster presentations  GENEVA andd AMSTERDAM, Nov. 3, 2023 /PRNewswire/ — iOnctura, a clinical-stage biotech developing selective cancer therapies against targets that play critical roles in multiple tumor survival pathways, today announces abstract data to be presented at the 65th American Society of Hematology (ASH) Annual Meeting and Exposition, […]

Cerebellar Haemangioblastoma with Leptomeningeal spread

Introduction Hemangioblastomas (HB) are neoplasms originating in the central nervous system (CNS) with a generally good clinical course and prognosis. They represent 1.5–2.5% of all intracranial neoplasms and 7–12% of posterior fossa tumors.1 In about 30% of cases, HB are associated with von Hippel-Lindau syndrome (VHL), an autosomal dominant disorder characterized by lesions in different […]

Suspected primary bone marrow T-cell lymphoid neoplasia causing paraneoplastic hypercalcemia in 11 dogs (2014–2021)

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ASXL1 mutation is a novel risk factor for bleeding in Philadelphia-negative myeloproliferative neoplasms

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Comparison of complications between laparoscopic and open gastrectomies for early gastric cancer by a nationwide propensity score-matched cohort study

Abstract The safety of laparoscopic gastrectomy compared with that of open surgery for the treatment of early gastric cancer (EGC) is unidentified on a national scale. We aimed to compare the morbidity between laparoscopic and open gastrectomies for pathological T1 gastric cancer based on nationwide survey data. Data of 14,076 patients who underwent gastric cancer […]

Machine learning-based prediction models for parathyroid carcinoma using pre-surgery cognitive function and clinical features

Abstract Patients with parathyroid carcinoma (PC) are often diagnosed postoperatively, due to incomplete resection during the initial surgery, resulting in poor outcomes. The aim of our study was to investigate the pre-surgery indicators of PC and try to develop a predictive model for PC utilizing machine learning. Evaluation of pre-surgery neuropsychological function and confirmation of […]

EXCEED-ET Study Evaluates Ropeginterferon alfa-2b-njf in ET

Lucia Masarova, MD, PhD, assistant professor, Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, discusses the rationale of the EXCEED-ET study (NCT05482971) of ropeginterferon alfa-2b-njf (Besremi) for patients with essential thrombocytopenia (ET). Transcription: 0:10 | The EXCEED-ET study is getting the ropeginterferon, which is the novel interferon into […]

Poster Presentation Monday, Dec. 11th 6 : 00-8

4181 Narazaciclib, a Differentiated CDK4/6 Antagonist, Prolongs Cell Cycle Arrest and Metabolomic Reprogramming, Enabling Restoration of Ibrutinib Sensitivity in Btki-Resistant Mantle Cell Lymphoma Program: Oral and Poster Abstracts Session: 605. Molecular Pharmacology and Drug Resistance: Lymphoid Neoplasms: Poster III Hematology Disease Topics & Pathways: apoptosis, Lymphomas, Combination therapy, Diseases, aggressive lymphoma, Therapies, metabolism, Lymphoid Malignancies, […]

Rigel Announces Poster Presentations at the 65th American Society of Hematology Annual Meeting and Exposition

— Growing body of data on REZLIDHIA® (olutasidenib) in mIDH1 relapsed or refractory (R/R) acute myeloid leukemia (AML) patients — — New data on olutasidenib in patients with mIDH1 myelodysplastic syndromes/neoplasms (MDS) — SOUTH SAN FRANCISCO, Calif., Nov. 2, 2023 /PRNewswire/ — Rigel Pharmaceuticals, Inc. (Nasdaq: RIGL) today announced the upcoming presentation of four posters highlighting […]