Shattuck Labs to Present Topline Data from Phase 1 A/B Clinical Trial of SL-172154 in Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML) and Higher-Risk Myelodysplastic Syndromes (HR-MDS) Patients
Oral presentation will showcase distinct preclinical profile for potent, selective MALT1 scaffolding inhibitor that is highly differentiated from MALT1 protease inhibitors BOSTON, Nov. 2, 2023 /PRNewswire/ — HotSpot Therapeutics, Inc., a biotechnology company pioneering the discovery and development of oral, small molecule allosteric therapies targeting regulatory sites on proteins referred to as “natural hotspots,” today […]
In a recent editorial published in Nutrients, researchers described the health benefits of regular exercise, a healthy diet, and adequate sleep. Study: Effects of Healthy Lifestyles on Chronic Diseases: Diet, Sleep and Exercise. Image Credit: Nok Lek Travel Lifestyle/Shutterstock.com Background The most impactful and controllable element influencing overall health and disease resilience is lifestyle. Chronic illness cases […]
1Wuxi School of Medicine, Jiangnan University, Wuxi, People’s Republic of China; 2Department of Cardiothoracic Surgery, Affiliated Hospital of Jiangnan University, Wuxi, People’s Republic of China; 3Department of Radiology, Huadong Sanatorium, Wuxi, People’s Republic of China Correspondence: Lei Jiang, Department of Radiology, Huadong Sanatorium, Wuxi, People’s Republic of China, Tel +86 13921272670, Email [email protected] Background: Lung […]
HPV distribution characteristics in patients with cervical lesions Of the 3674 patients with cervical lesions, 2744 were positive for HPV, giving a prevalence of 74.69% (95% CI 73.28–76.09%). The prevalence of HPV in CIN I, CIN II, CIN III, and ICC groups were 66.65% (1273/1910, 95% CI 64.53–68.77%), 80.78% (580/718, 95% CI 77.89–83.67%), 83.88% (483/576, […]
— Growing body of data on REZLIDHIA® (olutasidenib) in mIDH1 relapsed or refractory (R/R) acute myeloid leukemia (AML) patients — — New data on olutasidenib in patients with mIDH1 myelodysplastic syndromes/neoplasms (MDS) — SOUTH SAN FRANCISCO, Calif., Nov. 2, 2023 /PRNewswire/ — Rigel Pharmaceuticals, Inc. (Nasdaq: RIGL) today announced the upcoming presentation of four posters […]
Karyopharm Reports Third Quarter 2023 Financial Results and Highlights Recent Company Progress – Achieved Third Quarter 2023 Total Revenue of $36.0 Million and U.S. XPOVIO® (selinexor) Net Product Revenue of $30.2 Million – – Maintains Full Year 2023 Total Revenue Guidance of $145 Million to $160 Million, Including U.S. XPOVIO Net Product Revenue Guidance of […]
Preclinical data indicate that narazaciclib shows monotherapy and combination anti-tumor activity in ibrutinib-sensitive and resistant cells and xenograft models NEWTOWN, Pa., Nov. 02, 2023 (GLOBE NEWSWIRE) — Onconova Therapeutics, Inc. (NASDAQ: ONTX), (“Onconova” or “the Company”), a clinical-stage biopharmaceutical company focused on discovering and developing novel products for patients with cancer, today announced that Onconova […]
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Galluzzi L, Humeau J, Buqué A, Zitvogel L, Kroemer G. Immunostimulation with chemotherapy in the era of immune checkpoint inhibitors. Nat Rev Clin Oncol. 2020;17:725–41. https://doi.org/10.1038/s41571-020-0413-z. Article PubMed Google Scholar Carlino MS, Larkin J, Long GV. Immune checkpoint inhibitors in melanoma. The Lancet. 2021;398:1002–14. https://doi.org/10.1016/S0140-6736(21)01206-X. Article CAS Google Scholar Bagchi S, Yuan R, Engleman EG. […]