Category Archives: Cancer and neoplasms

Dr Kuykendall on Frontline Cytoreductive Therapies in Polycythemia Vera

Andrew Kuykendall, MD, assistant member, Department of Malignant Hematology, Moffitt Cancer Center, discusses frontline cytoreductive treatment options for patients with polycythemia vera. In the management of polycythemia vera, the choice of treatment with frontline cytoreductive therapies is primarily between pegylated interferon alfa-2a or hydroxyurea, 2 agents that possess distinct characteristics, Kuykendall says. Pegylated interferon alfa-2a […]

ESMO 2023: New Therapeutic Targets in Advanced Renal Cell Carinoma and Data from Sequencing Trials

(UroToday.com) The 2023 ESMO annual meeting included a session on optimizing overall survival in advanced renal cancer, featuring a presentation by Dr. Cristina Suarez Rodriguez discussing data from sequencing trials and new therapeutic targets. Dr. Suarez Rodriguez notes that there are several important definitions with regard to patterns of disease response to immune checkpoint inhibitors. […]

ESMO 2023: New Therapeutic Targets in Advanced Renal Cell Carcinoma (RCC) and Data from Sequencing Trials

(UroToday.com) The 2023 ESMO annual meeting included a session on optimizing overall survival in advanced renal cancer, featuring a presentation by Dr. Cristina Suarez Rodriguez discussing data from sequencing trials and new therapeutic targets. Dr. Suarez Rodriguez notes that there are several important definitions with regard to patterns of disease response to immune checkpoint inhibitors. […]

Cell-Free Liquid Biopsy Test for Ovarian Cancer Proves 91% Accurate

ovarian cancer | Image credit: Crystal light – stock.adobe.com A recent analysis investigating the use of an experimental cell-free DNA (cfDNA) liquid biopsy found that the test was 91% accurate at identifying early-stage epithelial ovarian cancer (EOC), a higher rate than that of other tests currently available. The study, published in Clinical Cancer Research, showed […]

Foundation Medicine Announces Acceptance of 11 Abstracts at the 2023 European Society for Medical Oncology (ESMO) Annual Meeting

CAMBRIDGE, Mass.–(BUSINESS WIRE)–Oct 19, 2023– Foundation Medicine, Inc., today announced that the company will present 11 abstracts demonstrating the value of high-quality biomarker tests to inform cancer care at the 2023 European Society for Medical Oncology (ESMO) Annual Meeting from October 20-24 in Madrid, Spain.

Higher Leptin Levels, Body Fat Linked to MDS in Study

A study accepted for publication in the British Journal of Nutrition explores links among measures of leptin, adiponectin, and adiposity in patients with myelodysplastic syndrome (MDS). The authors, all from the Federal University of Ceará, in Fortaleza, Brazil, found significant links among the measures, which they said showed the need for “comprehensive and systematic evaluation […]

Roswell Park Licenses Rapid, Comprehensive Blood Test To Agilent, A Global Leader In The Life Sciences Market

An advanced, high-speed blood cancer test developed at Roswell Park Comprehensive Cancer Center has been licensed for commercial development by Agilent Technologies Inc. The PanHeme assay for blood cancers slashes wait time for results from 3-4 weeks to under 72 hours, enabling rapid deployment of therapies most likely to benefit the patient. Buffalo, NY /PRNewswire-PRWeb/ […]

Recurrent chemotherapy treated IDCT

1Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China; 2Department of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China Correspondence: Jing Xiong, Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, […]

Long-term outcomes of endoscopic resection for duodenal neuroendocrine tumors

Abstract Duodenal neuroendocrine tumors (d-NETs) ≤ 10 mm in size, confined to the submucosal layer, without lymph node or distant metastasis, can be treated safely and effectively by endoscopic management. However, most results are based on limited data and short follow-up outcomes. Herein, we aimed to evaluate the short-term and long-term outcomes of endoscopic resection for d-NETs. We […]

Multi-system diseases and death trajectory of metabolic dysfunction-associated fatty liver disease: findings from the UK Biobank

The present study provides a panoramic view of temporal disease and death trajectories of MAFLD in the community-dwelling population of the UK Biobank cohort study. MAFLD was proved to be related to 113 medical conditions and eight causes of death when limiting disease incidence to ≥ 1%. The network of these diseases originates from asthma, diabetes, hypothyroid […]