Category Archives: Cancer and neoplasms

Can organoid model reveal a key role of EVs in tumors

Introduction Extracellular vesicles (EVs) are small membrane-bound vesicles that are released by cells into the extracellular environment.1 They contain a variety of bioactive molecules, including proteins, lipids, and nucleic acids, and are involved in intercellular communication and the regulation of various physiological and pathological processes.2 EVs are a group of nanovesicles that can be mainly […]

Correlations between iodine uptake, invasive CT features and pleural invasion in adenocarcinomas with pleural contact

Abstract Pleural contact in lung cancers does not always imply pleural invasion (PI). This study was designed to determine whether specific invasive CT characteristics or iodine uptake can aid in the prediction of PI. The sample population comprised patients with resected solid lung adenocarcinomas between April 2019 and May 2022. All participants underwent a contrast […]

Computer-aided diagnosis for screening of lower extremity lymphedema in pelvic computed tomography images using deep learning

Abstract Lower extremity lymphedema (LEL) is a common complication after gynecological cancer treatment, which significantly reduces the quality of life. While early diagnosis and intervention can prevent severe complications, there is currently no consensus on the optimal screening strategy for postoperative LEL. In this study, we developed a computer-aided diagnosis (CAD) software for LEL screening […]

KIT Inhibitors Lead to Shift in Treatment of Systemic Mastocytosis

The hematologic neoplasm systemic mastocytosis (SM) is marked by the clonal proliferation of mast cells in the skin, bone marrow, gastrointestinal tract, spleen, and/or liver, caused by an activating KIT mutation in the KIT gene.1 Notably, in approximately 95% of patients, this mutation is identified as KIT D816V in exon 17, and in most instances, […]

Shih Tzu puppy shows improvement with stem cell therapy

After noticing Oliver, a 10-month-old Shih Tzu, was limping, his family decided that it was time to take him to his veterinarian, Kimberly Carlson, DVM, DACVS, from Lenity Vet Specialists and Emergency Care in San Mateo, California. Carlson determined Oliver was suffering from elbow dysplasia and arthritis in both is front legs and recommended surgical […]

Karyopharm to Present Selinexor Data at the 2023 International Myeloma Society Annual Meeting and European Society of Gynaecological Oncology 2023 Annual Meetings

NEWTON, Mass., Sept. 26, 2023 /PRNewswire/ — Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that several abstracts detailing new selinexor data have been selected to be presented at the 2023 International Myeloma Society (IMS) Annual Meeting, being held September 27-30 in Athens, Greece. In addition, exploratory subgroup analyses […]