Category Archives: Cancer and neoplasms

Dr Islam on the Limited Use of Ibrutinib in CLL

Prioty Islam, MD, MSc, attending physician, medical oncologist, Leukemia, Division of Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, discusses the current status of the first-generation BTK inhibitor ibrutinib (Imbruvica) following the FDA approvals of next-generation BTK inhibitors in patients with chronic lymphocytic leukemia (CLL) and expands on the few instances in the clinic where she […]

NEW SURVEY FROM THE LEUKEMIA & LYMPHOMA SOCIETY (LLS) REVEALS LOW AWARENESS ABOUT BLOOD CANCERS

Nearly 80 and 90 percent of adults respectively don’t associate lymphoma and myeloma as types of blood cancer; LLS provides free blood cancer education and resources for all and personalized support for patients, survivors, families, and caregivers RYE BROOK, N.Y., Sept. 1, 2023 /PRNewswire/ — While a majority of adults recognize leukemia as a blood cancer, […]

Karyopharm Appoints Zhen Su, MD, MBA to its Board of Directors

NEWTON, Mass., Sept. 1, 2023 /PRNewswire/ — Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced the appointment of Zhen Su, MD, MBA, to its Board of Directors, effective August 31, 2023. Dr. Su is currently Chief Executive Officer and a member of the Board of Directors at Marengo […]

‘Raising awareness of blood cancer symptoms saves lives. It’s as simple as that’

Life with Leukaemia: A family’s story of navigating the emotional, physical and financial challenges of living with blood cancer, by Amy Atkinson September is Blood Cancer Awareness Month. Blood Cancer is the fifth most common cancer in the UK and the third biggest killer. Let’s work together towards a future that is brighter for blood […]

Breast Cancer Mutations HER2V777L and PIK3CAH1047R Activate the p21–CDK4/6–Cyclin D1 Axis to Drive Tumorigenesis and Drug Resistance

Citation Xiaoqing Cheng, Yirui Sun, Maureen Highkin, Nagalaxmi Vemalapally, Xiaohua Jin, Brandon Zhou, Julie L. Prior, Ashley R. Tipton, Shunqiang Li, Anton Iliuk, Samuel Achilefu, Ian S. Hagemann, John R. Edwards, Ron Bose; Breast Cancer Mutations HER2V777L and PIK3CAH1047R Activate the p21–CDK4/6–Cyclin D1 Axis to Drive Tumorigenesis and Drug Resistance. Cancer Res 1 September 2023; […]

Estimating disparities in breast cancer screening programs towards mortality, case fatality, and DALYs across BRICS-plus

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–49. Article  PubMed  Google Scholar  Barba D, León-Sosa A, Lugo P, Suquillo D, Torres F, Surre F, et al. Breast […]

Aspartame safety review by the WHO: a short story about a tempest in a teapot…

Thursday, August 31, 2023 On July 14, 2023, the World Health Organization (WHO) announced the results of the dual review of the well-known sugar-substitute aspartame by the Joint FAO/WHO Expert Committee on Food Additives (JECFA) and the International Agency for Research on Cancer (IARC), two scientific bodies with different missions, but with one common parent: […]

Reply to: Addressing racial and ethnic disparities in AACR project GENIE

replying to Sweeney et al. npj Precision Oncology https://doi.org/10.1038/s41698-023-00425-5 (2023) We thank Sweeney et al. for their comments regarding our recent article evaluating the representation of racial/ethnic minority groups in the AACR Project GENIE for precision oncology research. Our findings1 suggest that this real-world biorepository—while providing a wealth of clinical-genomic data—may not accurately reflect the […]