Introduction Neutrophils are the most abundant population of immune cells in human peripheral circulation, and the defense of the innate immune system at the frontline against invading pathogens.1–4 Notwithstanding, the roles played by neutrophils in regulating tumor immunity by interacting with other immune cells in the tumor microenvironment (TME) had been ignored for a long […]
Menarini Group Announces New Data on ORSERDU® (elacestrant) at the 2023 San Antonio Breast Cancer Symposium and on ELZONRIS® (tagraxofusp-erzs) at the 65th American Society of Hematology Annual Meet
Alexander Spira MD, PhD, FACP The investigational oral treatment RMC-6236 appeared safe and tolerable, alongside a reduction in tumor growth for patients with mutant solid tumors harboring KRAS G12X mutations across various cancer types. Investigators conducted a phase 1/1b multicenter open-label study trial (NCT05379985) to assess the dosage, safety, and efficacy of RMC-6236, according to […]
Current patients had early access to game-changing diagnostic tool. A new Roswell Park Comprehensive Cancer Center innovation has just gone global. Called PanHeme, it’s a test that uses next-generation gene sequencing technology to diagnose blood cancers like leukemia, lymphoma and multiple myeloma more precisely — identifying mutations in hundreds of genes — in under 72 […]
Introduction Vasopressin, the antidiuretic hormone in humans, is also an important hormonal component in the regulation of blood pressure.1 The peptide is normally produced by neurons of the hypothalamus under regulation, principally through changes in the osmolality of the blood. The expression of the normal vasopressin gene is also a common feature of all small-cell […]
Previous story: ONYX Hospitality Group Shines Bright at ITB Asia 2023, Unveiling Its Potential Next story: Quote on Women’s Entrepreneurship Day from Hardika Shah, Founder & CEO, Kinara Capital Rare Types of Pancreatic Cancer: Understanding and Treatment Published on November 20, 2023 Dr. Ajay Mehta, Director and Head Surgical Oncology, HCG Cancer Centre, Nagpur Pancreatic […]
Abstract Context: There is a growing interest about the role of radical prostatectomy (RP) in local cancer control in oligometastatic prostate cancer (PCa). Purpose: To evaluate the oncological and functional outcomes of RP in the management of oligometastatic PCa through a systematic review. Methods: A systematic review search was performed and the following bibliographic databases […]
Abstract Tumor-infiltrating lymphocytes (TIL) have been suggested as an important prognostic marker in colorectal cancer, but assessment usually requires additional tissue processing and interpretational efforts. The aim of this study is to assess the clinical significance of artificial intelligence (AI)-powered spatial TIL analysis using only a hematoxylin and eosin (H&E)-stained whole-slide image (WSI) for the […]
