Category Archives: Cancer and neoplasms

Routine next-generation sequencing can identify BRAF mutations in synovial sarcoma

A new case report was published in Oncotarget’s Volume 14 on July 7, 2023, entitled, “Intrathoracic synovial sarcoma with BRAF V600E mutation.” Synovial sarcoma (SS) is a highly malignant mesenchymal tumor that occurs mainly in adolescents and young adults. The treatment of SS is multimodal, involving surgery, radiotherapy and chemotherapy. The overall prognosis is generally […]

Famous Singer and Actress, 58, Mistook Skin Cancer for Eczema Before Diagnosis

Singer and actress Coleen Nolan, 58, admits her dismissive attitude nearly cost her a diagnosis of basal cell carcinoma which is a type of skin cancer. Nolan has basal cell carcinoma on her shoulder and melanoma on her face she first thought was eczema. Her discovery of skin cancer highlights the importance of regularly checking […]

Case Report: Intrathoracic synovial sarcoma with BRAF V600E mutation

image: Figure 2: (A) Axial T2 MR shows a heterogeneous mass in the cardiophrenic space with evidence of anterior chest wall invasion and intercostal invasion. (B) Axial T2 MR shows 35 % of reduction in size of the mass in the cardiophrenic space. view more  Credit: 2023 Russo et al. “The prognosis of recurrent/metastatic SS remains […]

Can Smartphones Give You Brain Cancer? A New Study Tries to Answer This Age-old Question

Key Takeaways People have long wondered whether cell phone use might cause brain cancer, but there’s been no evidence to prove this connection. A new 20-year study from Taiwan aimed to answer this question, but it only added to the mountain of inconclusive research after finding a positive but ultimately weak, non-significant association between mobile […]

Why Black Americans Are at Higher Risk for Multiple Myeloma

Statistically speaking, multiple myeloma is more survivable than ever, according to Memorial Sloan Kettering Cancer Center. Now the not-so-good news: Your race could affect your outlook. Black Americans are about twice as likely to be diagnosed with multiple myeloma and to die from this cancer as white Americans, according to the American Cancer Society. That’s […]

Delayed HRQOL Outcomes Are Observed With Lutetium Lu 177 Vipivotide Tetraxetan in mCRPC

Delayed onset of heath-related quality-of-life (HRQOL) outcomes were observed with the addition of lutetium Lu 177 vipivotide tetraxetan (Pluvicto; formerly 177Lu-PSMA-617) among patients with metastatic castration-resistant prostate cancer (mCRPC). Findings from the phase 3 VISION trial (NCT03511664) published in Lancet Oncology, compared HRQOL and skeletal events of the combination of lutetium Lu 177 vipivotide tetraxetan […]

Childhood brain tumor diagnosis fuels commitment to future generations

As he approaches his 30th birthday, Harrison Elias often looks around and cannot believe how far he has come. After completing his master’s degree in exercise science/strength and conditioning at Springfield College and stints as a Division I college strength and conditioning coach at the University of Rhode Island and Boston College, he is now […]

The potential prognostic role of AhRR and PPP1R3C expression in serous ovarian cancer

A recent study published in the International Journal of Molecular Sciences evaluated genes with copy number (CN) alterations (CNAs) to identify biomarkers for ovarian cancer (OC) prognosis. Study: AhRR and PPP1R3C: Potential Prognostic Biomarkers for Serous Ovarian Cancer. Image Credit: ESBProfessional/Shutterstock.com Background OC encompasses a set of heterogeneous neoplasms with distinct biological and morphological features. OC can […]

Physiological Effects of Isotretinoin

Introduction Acne vulgaris (AV) is a chronic, immune-mediated, multifactorial inflammatory disease affecting the hair sebaceous gland units,1–3 which is one of the most common skin disorder afflicting adolescents worldwide.4,5 Isotretinoin (ISO) is a powerful vitamin A derivative, and it is the only possible treatment for permanent remission of acne. Its action mechanism is to normalize […]