Category Archives: Cancer and neoplasms

Lucia Masarova, MD, PhD An overperforming JAK-STAT pathway, including the presence of JAK2, CALR, and MPL gene mutations leads to high platelet count in patients with essential thrombocytopenia (ET).1 Safe and potent therapies are needed for these populations, especially for those requiring cytoreduction, regardless of their prior exposure to hydroxyurea and/or anagrelide, according to Lucia […]

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The development of head and neck cancer is increasingly linked to HPV infection, which is a sexually transmitted disease. Oropharyngeal cancer is a type of head and neck cancer that is associated with preconceptions regarding the high-risk sexual behavior of the affected individuals. Circumventing some potential sources of bias related to case-control studies, researchers at […]

Rapidly increasing risk factors for cancer mortality worldwide, 1990–2019 The number of cancer deaths attributable to HFPG worldwide in 2019 was 419,340 (95% CI 115,730–848,480). In the global range, tobacco consumption, dietary risks, and alcohol consumption (top three from high to low) were still risk factors that caused the most cancer deaths in 2019 when […]

George Nahas, DO, attending physician, and hematology and oncology specialist at Miami Cancer Institute, discusses recent and ongoing research that has impacted the current treatment landscape for patients with multiple myeloma. According to Nahas, the use of immunotherapy has proven to be beneficial in this space. Specifically, treatment with chimeric antigen receptor (CAR) T-cell therapy […]

Photo: Tom Eversley (Shutterstock) The World Health Organization has said three different things about aspartame this year. First, they said not to use sweeteners like aspartame for weight loss. Next, they designated aspartame, the sweetener in Diet Coke, a “possible” carcinogen. Now, the branch responsible for deciding which food additives are safe has confirmed that […]

Currently, the low incidence rate and high heterogeneity hindered further investigation of GNEC [15]. Thus, we created and validated a nomogram to predict the 1-, 3-, and 5-year CSS of surgical GNEC patients based on the SEER database. The model demonstrated improved prediction ability compared with the 8th AJCC criteria. We then developed a novel […]

Imaging mass cytometry (IMC) may help to analyze tumor-immune evasion cell networks in clear cell renal cell carcinoma (RCC) samples, according to Hartland W. Jackson, PhD, who indicated that the new technology may allow for scaling single cell biology to look at large clinical cohorts. In a presentation during the 2023 Kidney Cancer Research Summit […]

The overall incidence rate of pediatric cancer increased on average from 2003 to 2019, peaking in 2016, according to a study published online July 11 in the Journal of the National Cancer Institute. David A. Siegel, M.D., M.P.H., from the U.S. Centers for Disease Control and Prevention in Atlanta, and colleagues updated cancer incidence rates […]