Papillary craniopharyngiomas (PCPs) are a rare type of brain tumor that cause substantial morbidity for patients. While surgery and radiation are often used to treat PCPs, incomplete removal of the tumor and toxicity from radiation can leave patients with life-long health challenges after treatment, including neuroendocrine dysfunction or vision or memory loss. Investigators from the […]
Category Archives: Cancer and neoplasms
Metastatic disease causes most deaths from cancer but how the cancer genome evolves during the progression from primary to secondary disease remains an important unanswered question. Reporting in Nature, Martínez-Jiménez et al. re-analyzed whole-genome sequences from 7,108 tumors across 23 cancer types comprising untreated primary tumors and (unmatched) treated secondary tumors. Their results showed that […]
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Jul
The U.S. still lags in research on benign breast disease—like cysts, scar tissue and tumors—because it’s seen as “a woman’s disease.” Most women have benign (non-cancerous) breast conditions. These conditions are not life-threatening, but some are linked with a higher risk of getting breast cancer later on. (Andres R / Getty Images) Paulette Kennedy did […]
Cancer and neoplasms
New discovery in t-cell research could lead to improved treatment of solid tumors
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Jul
Jul
SINGAPORE – A local study led by the Agency for Science, Technology and Research (A*STAR) discovered that by inhibiting the function of two proteins, G9a and GLP, during the cell therapy production process, immune cells could become more effective in combatting cancer. These findings, published in the journal Nature Communications, can help advance the development […]
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Jul
Jul
Cyclophosphamide injections are indicated for use in various leukemias, including chronic lymphocytic leukemia, chronic granulocytic leukemia, and acute lymphoblastic leukemia. The FDA has approved a new drug application for a ready-to-dilute cyclophosphamide injection intended for use in combination with other therapies for patients with hematologic cancers, according to a press release from Nekavar Injectables Inc.1 […]
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Jun
Antibody drug conjugates have existed for years, but several recent advances are helping to refine how these cancer drugs work, expanding our understanding to help overcome their challenges and, ultimately, extending their benefit to more patients. “Antibody drug conjugates are an exciting field of drug development,” says Funda Meric-Bernstam, M.D., chair of Investigational Cancer Therapeutics. […]