Category Archives: Cardiovascular

Spanish scientists discover a promising therapeutic target for cardiac arrhythmias

image:  Guadalupe Sabio, Rafael Romero, Juan Antonio López, Alfonso Mora, Francisco Miguel Cruz, José Jalife, Luis Guillermo Leiva, Jesús Vázquez y Marta León. view more  Credit: CNIC A study led by Guadalupe Sabio and José Jalife at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid has identified a new signaling mechanism implicated in the […]

High doses of ADHD medication could increase risk of heart disease

Long-term treatment of ADHD may be linked to cardiovascular disease, but many people stop taking these medications in the first year. ADVERTISEMENT People who take medication for attention deficit hyperactivity disorder (ADHD) for long periods of time and at high doses may be at an increased risk of some cardiovascular diseases, new research suggests. ADHD […]

Association of body mass index and long-term mortality in patients from nationwide LIPIDOGRAM 2004–2015 cohort studies: no obesity paradox?

Kenchaiah S, Evans JC, Levy D, et al. Obesity and the risk of heart failure. N Engl J Med. 2002;347(5):59–60. https://doi.org/10.1056/NEJMOA020245. Article  Google Scholar  Manson JE, Colditz GA, Stampfer MJ, et al. A prospective study of obesity and risk of coronary heart disease in women. N Engl J Med. 2010;322(13):882–9. https://doi.org/10.1056/NEJM199003293221303. Article  Google Scholar  Yousufuddin […]

Safety and efficacy of bempedoic acid: a systematic review and meta-analysis of randomised controlled trials

Townsend N, Kazakiewicz D, Lucy Wright F, et al. Epidemiology of cardiovascular disease in Europe. Nat Rev Cardiol. 2022;19:133–43. Article  PubMed  Google Scholar  Roth GA, Abate D, Abate KH, et al. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden […]

Prognostic value of triglyceride-glucose index in patients with chronic coronary syndrome undergoing percutaneous coronary intervention

Tsao CW, Aday AW, Almarzooq ZI, Alonso A, Beaton AZ, Bittencourt MS, et al. Heart Disease and Stroke statistics-2022 update: a report from the American Heart Association. Circulation. 2022;145(8):e153–e639. https://doi.org/10.1161/CIR.0000000000001052. Epub 2022 Jan 26. Erratum in: Circulation. 2022;145(8):e153-e639. doi:10.1161/CIR.0000000000001052. Article  PubMed  Google Scholar  GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 Diseases and […]

Access is key barrier to cardiac rehab.

Newswise — Philadelphia, November 28, 2023 – Noted experts in cardiovascular rehabilitation attending the Third Jim Pattison-Mazankowski Alberta Heart Institute Cardiac Rehabilitation Symposium (Banff, April 21-23, 2023) observed that although cardiac rehabilitation benefits diverse groups of patients and affords the most cost-effective prevention for recurrent events, it is grossly underutilized globally. They concluded that access is […]

Novartis upgrades mid-term sales growth guidance, showcases its differentiated innovative medicines strategy and robust pipeline at R&D Day

Ad hoc announcement pursuant to Art. 53 LR  ‘Pure-play’ innovative medicines strategy focused on four therapeutic areas and five technology platforms, which offer potential for consistent growth Mid-term sales guidance upgrade to 5% CAGR (2022-27), with core operating income margin of ~40%+ by 2027, driven by continued strong momentum of key growth drivers   Confidence to […]

Advanced glycation end products measured by skin autofluorescence and subclinical cardiovascular disease: the Rotterdam Study

Collaborators GCD. GBD 2017 Causes of Death Collaborators. Global, regional, and national age-sex-specific mortality for 282 causes of death in;195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017 (vol 392, pg 1736, 2018). Lancet. 2018;392(10160):2170. Google Scholar  Fuchs A, Kuhl JT, Sigvardsen PE, Afzal S, Knudsen AD, Moller […]

Examining disparities in cardiovascular disease prevention strategies and incidence rates between urban and rural populations: insights from Kazakhstan

Abstract Kazakhstan is experiencing a high burden of cardiovascular disease (CVD), and the country has implemented a range of strategies aimed at controlling CVD. The study aims to conduct a content analysis of the policies implemented in the country and augment it with an analysis of official statistics over a 15-year period, from 2006 to […]

Triglyceride-glucose index, renal function and cardiovascular disease: a national cohort study

Adeva-Andany MM, Martínez-Rodríguez J, González-Lucán M, Fernández-Fernández C, Castro-Quintela E. Insulin resistance is a cardiovascular risk factor in humans. Diabetes Metab Syndr. 2019;13(2):1449–55. PubMed  Google Scholar  Cockwell Paul, Fisher Lori-Ann. Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2020;395(10225):709–33. Google Scholar  […]