Category Archives: Congenital disorders

Abstract Lissencephaly (LIS) is a malformation of cortical development due to deficient neuronal migration and abnormal formation of cerebral convolutions or gyri. Thirty-one LIS-associated genes have been previously described. Recently, biallelic pathogenic variants in CRADD and PIDD1, have associated with LIS impacting the previously established role of the PIDDosome in activating caspase-2. In this report, […]

Pneumonia Etiology Research for Child Health Study G. Causes of severe Pneumonia requiring hospital admission in children without HIV Infection from Africa and Asia: the PERCH multi-country case-control study. Lancet. 2019;394(10200):757–79. Article  Google Scholar  Falsey AR. Current management of parainfluenza pneumonitis in immunocompromised patients: a review. Infect Drug Resist. 2012;5:121–7. Article  PubMed  PubMed Central  Google […]

Due to shared lifestyle risk factors, aortic stenosis can sometimes be mistaken for myocardial infarction, more commonly known as a heart attack. The latter often arises when blood flow to the heart is reduced or blocked by atherosclerosis, resulting in poor oxygen supply to the heart muscle. Without the prompt restoration of blood flow, the […]

Significant gaps in crucial information surrounding child deaths are resulting in “very little” accurate data being available, according to the National Office of Clinical Audit (NOCA). The NOCA said the lack of a centralised database for the accurate analysis and timely reporting of data related to child deaths has been a “critical challenge”. The issue […]

The pesticides not only affect the health of those who consume these farm produce, but also the farmers who use them Success in agriculture is closely linked to increased use of pesticides. Even though humans have been using chemicals for controlling pests since time immemorial, the rampant use of toxic chemicals like arsenic, mercury, lead […]

I don’t think I’ve analyzed this paper on my site, but, since it came out recently, it’s become well known among rational biologists for being tendentious, ideologically based, and largely incoherent, something you might intuit from its title. You can read it by clicking on the screenshot below: The paper’s object is to dismantle the […]

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Introduction Retinopathy of prematurity (ROP), a vasoproliferative disorder of the immature retina, is currently one of the main causes of blindness or visual impairment of preterm infants, also related to long-term neurological and cognitive development disorders.1 Recent research showed that with the increase of the survival rate of preterm infants, especially very low birth weight […]