Category Archives: Congenital disorders

Scientists at CeMM, Max Perutz Labs, and St. Anna Children’s Cancer Research Institute in Vienna have achieved a significant advancement in the research of rare immune system disorders. Through a network-based approach, they have reclassified approximately 200 rare diseases. Initial comparisons with clinical data already demonstrate how this can enhance the prediction of treatment efficacy. […]

The AutoCore and common, polygenic autoimmune and autoinflammatory diseases. This figure illustrates the relative position of the AutoCore within the context of the network modules of common, chronic inflammatory disorders such as inflammatory bowel disease, rheumatoid arthritis and systemic lupus erythematosus. We find that the AutoCore lies at the center of these diseases connecting them […]

1-Sep-2023 A deficiency in folate (vitamin B9), the well-known “pregnancy vitamin,” impacts foetal development and increases the risk of congenital brain and spine disabilities. Less discussed is its role in promoting fertility. In essence, folate can be called “the family vitamin” As a starting point, notes Lorena Carboni, Senior Scientific Communication Specialist and Product Manager […]

Dr. Lucky GuptaCongenital anomalies are defined as structural or functional disorders that develop prenatally and may be identified before birth, at birth, or later in life. Major congenital anomalies are defined as anomalies with significant effect on life expectancy and they occur in 2-3% of live births and in 20-30% of stillbirths. Not all anomalies […]

India has a long way to go when it comes to indigenously developing tools for cardiac care. Though there has been significant improvement in manufacturing and global players tying up with Indian players, it is a long journey ahead. Artificial Intelligence (AI) and Machine learning-based tools are being touted as the future of cardiac care […]

Specialty

Abstract Recent advancements in gene supplementation therapy are expanding the options for the treatment of neurological disorders. Among the available delivery vehicles, adeno-associated virus (AAV) is often the favoured vector. However, the results have been variable, with some trials dramatically altering the course of disease whereas others have shown negligible efficacy or even unforeseen toxicity. […]