Category Archives: Infection

Abstract Chickens genetically resistant to avian influenza could prevent future outbreaks. In chickens, influenza A virus (IAV) relies on host protein ANP32A. Here we use CRISPR/Cas9 to generate homozygous gene edited (GE) chickens containing two ANP32A amino acid substitutions that prevent viral polymerase interaction. After IAV challenge, 9/10 edited chickens remain uninfected. Challenge with a […]

October 10, 2023 3 min read Source/Disclosures Disclosures: Regan reports support from a National Health and Medical Research Council early career fellowship. Edwards reports numerous memberships on data safety and monitoring boards, and consulting for Bionet, Dynavax and IBM. Please see the study for all other authors’ relevant financial disclosures. ADD TOPIC TO EMAIL ALERTS […]

By taking a strategic approach to antimicrobial stewardship and having evidence-based resources that provide current information on infections and appropriate treatments, healthcare leaders can help guide their clinicians to take steps toward combating antimicrobial resistance. The five ‘Ds’ of antimicrobial stewardship Antimicrobial overuse and misuse are the main drivers of antimicrobial resistance, a global threat […]

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KETTERING — Whooping cough is making its way into the Miami Valley as Kettering Schools confirmed that they have two cases. >>RELATED: Case of whooping cough detected at Kettering school A letter was sent to parents with kids at Kettering City Schools on Monday, warning them that the whooping cough has been detected. “This time […]

Photo: Irina Bg (Shutterstock) You’ve heard of “long COVID,” but COVID isn’t the only illness that can cause lasting symptoms. Other respiratory infections, including colds, flu, and pneumonia, seem to sometimes trigger a “long” version as well. This may not be shocking news if you’ve ever noticed a cough or body aches sticking around for some […]

What You Should Know The FDA’s acceptance of the New Drug Application (NDA) for ceftobiprole, submitted in August, could signifies a significant step forward in addressing severe bacterial infections. Ceftobiprole was designated as a candidate for the US Generate Antibiotics Incentives Now (GAIN) Act, which facilitates the development of new antimicrobial drugs. Ceftobiprole demonstrated noninferiority […]

Since COVID-19 began spreading in earnest in 2020, some people experienced a variety of symptoms months after their initial infection.  Oftentimes, long COVID symptoms come after mild cases of acute COVID-19. Generally, mild cases of COVID-19 mimic a common cold.  Researchers in Great Britain wanted to know if common colds can cause lingering effects similar […]

<div data-thumb="https://scx1.b-cdn.net/csz/news/tmb/2023/molecular-mechanisms-o.jpg" data-src="https://scx2.b-cdn.net/gfx/news/hires/2023/molecular-mechanisms-o.jpg" data-sub-html="Khd4-Ada-Gfp editing sites are highly reproducible. (A) Overview of the hyperTRIBE workflow. Reproducible editing sites overlapped between the two independent biological replicates of the Khd4-Ada-Gfp (blue) and control-Ada (gray) data were compared with each other (#1,2- replicates 1 and 2). Only editing events with 5% editing were used for the analysis. (B) […]

West Nile virus (Adobe Stock 496441812 by Dr_Microbe) Here in the United States, we’ve all noticed how hot it was this past summer. Along with the heat came disproportionate amounts of rainfall in some areas of the country. In the eastern US, many extreme rainfall events resulted in residual pools of stagnant water throughout the […]