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Category Archives: Infection
Abstract Lower respiratory tract infections caused by Streptococcus pneumoniae (Spn) are a leading cause of death globally. Here we investigate the bronchial epithelial cellular response to Spn infection on a transcriptomic, proteomic and metabolic level. We found the NAD+ salvage pathway to be dysregulated upon infection in a cell line model, primary human lung tissue […]
Carbapenem-resistant Enterobacterales (CREs) are a dominant threat to patient health in healthcare settings worldwide. CRE strains consistently have limited therapeutic options, often associated with increased toxicities, and require prolonged treatment, leading to a higher cost burden than carbapenem-susceptible strains [9]. In this study, 61.9% of carbapenem-resistant isolates were K. pneumoniae. Compared to each other, 38.1% […]
October 02, 2023 3 min read Source/Disclosures Published by: Disclosures: Polish National Agency for Academic Exchange supported the study. Lancman reports advisory board roles with Janssen and Pfizer. Please see the study for all other authors’ relevant financial disclosures. Garfall reports funding and/or consulting fees from Bristol Myers Squibb, CRISPR Therapeutics, GSK, Janssen, Legend Bio, […]
The Arizona Department of Health Services (ADHS), alongside the Centers for Disease Control and Prevention (CDC), recognized Fungal Disease Awareness Week Sept. 18-22, an annual event that highlights the growing challenges surrounding the spread of infectious fungi across the United States, . While many different types of fungal diseases call Arizona home, one of the most common is Valley fever. […]
Little boy touching painful neck: ©Krakenimages.com-stock.adobe.com Respiratory infections are a leading reason for sick visits in pediatric practice, whether they are caused by bacteria, viruses, or other chronic issues—but how best to treat these infections remains a source of debate, both among health care professions and between parents and physicians.1 Pediatricians know that targeted treatments […]
October 1, 2023 News Article Check out important news you might have missed including the expanded indication for remdesivir to those with severe hepatic impairment; a small study shows that SARS-CoV-2 infects coronary arteries and increases plaque Inflammation; and some antibiotics are associated with C diff Infection. Related Videos Related Content Related Content
According to a recent study led by scientists at the Harvard Pilgrim Health Care Institute, SARS-CoV-2 accounted for 1 in 6 occurrences of sepsis over the first 33 months of the COVID-19 pandemic, highlighting the importance of viral sepsis. The end of Sepsis Awareness Month, as well as the publishing of the report, serve as […]
Antibiotics treat infections caused by bacteria — but bacteria can evolve to resist these essential drugs. Over time, the misuse of antibiotics has rapidly accelerated the spread of such resistant germs, and widely used antibiotics are becoming less effective. So until alternative drugs to antibiotics are developed, how can we slow the rise of bacterial […]