Category Archives: Infection

LpxC inhibitor eliminates bacterial infections

RESEARCH HIGHLIGHT 04 September 2023 Sarah Crunkhorn Sarah Crunkhorn .readcube-buybox { display: none !important;} UDP-3-O-acyl-N-acetylglucosamine deacetylase (LpxC) is a rate-limiting enzyme in the lipid A biosynthetic pathway that is essential for most pathogenic Gram-negative bacteria. Although LpxC is an attractive antibacterial target, few inhibitors have reached clinical trials, largely due to limited efficacy and dose-limiting […]

Virtual wards: NICE sets out guidance on managing acute respiratory infections at home

Jacqui Wise Kent More people with acute respiratory infections could be treated outside hospitals in respiratory hubs or virtual wards this winter, advises new guidance from the UK National Institute for Health and Care Excellence.1 NHS England has prioritised the expansion of virtual ward capacity as a way to relieve pressure on hospitals,2 but health […]

An intercellular bridge for chikungunya virus transmission

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that causes chikungunya fever. Currently there are no vaccines or antiviral therapies available for the prevention or treatment of CHIKV infections. Infections by alphaviruses involve both free virus particles (that is, the release of new viral particles from the infected cell into the extracellular fluid, to then infect […]

Bartonella infections are prevalent in rodents despite efficient immune responses

We profiled the dynamics of a natural Bartonella isolate as it infected captive individuals of three rodent species that coexist in nature. We also tracked Bartonella-specific IgG antibody levels in these animals over 140 days after the first inoculation and 60 additional days following their re-exposure to the same strain. In nature, the mean longevity of […]

Covid cases nearly DOUBLE with estimated 93,000 new infections

Covid cases nearly DOUBLE in a month with estimates showing almost 93,000 new infections each day Data shows cases have increased by 50,000 in September from start of August The rise in cases comes alongside the emergence of a new Covid variant  By Kate Pickles Health Editor Updated: 20:00 EDT, 3 September 2023

‘7-day fever’, with severe symptoms, lays Kol low | Kolkata News

KOLKATA: The “seven-day fever” has made a comeback after a brief lull in the spate of viral infections, with severe symptoms often overlapping with dengue. While in its first spell, low-grade fever, cough and body ache were the dominant symptoms, this time, most have been struck by high fever, severe body ache, muscle pain, nausea […]

At least 5 deaths from flesh-eating bacteria in Connecticut, New York, North Carolina

The US Centers for Disease Control and Prevention issued a national health alert Friday to warn clinicians to be on the lookout for infections with the flesh-eating bacteria Vibrio vulnificus. During July and August, as the US saw widespread heatwaves and above-average coastal sea surface temperatures, Connecticut, New York and North Carolina reported more severe […]

Wisconsin deer farm infected with fatal brain disease

A deer farm in Wisconsin is under quarantine after testing positive for chronic wasting disease (CWD), a highly contagious and fatal brain disease. Scientists with the National Veterinary Services Laboratories in Ames, Iowa, confirmed that samples from a three-year-old doe tested positive for the neurological disease, the Wisconsin Department of Agriculture announced Thursday. The 150-acre […]

Flesh-Eating Bacteria Infections Pose Growing Threat Nationwide, CDC Warns

Vibrio vulnificus infections have killed at least 13 people on the Eastern Seaboard this year and cause an estimated 80,000 illnesses annually in the United States. Most people get infected with Vibrio by eating raw or undercooked shellfish, particularly oysters, the CDC said in the advisory which was issued on Friday, Sept. 1. Vibrio naturally live […]

Zika Infections Escalating in 2023

Washington DC (Precision Vaccinations News) During the recent pandemic, a seldom discussed mosquito-borne virus was confirmed in 89 countries globally. Although incidence levels of the Zika virus remained low, significant increases have been observed in some countries. Outbreaks of Zika in the region of the Americas have highlighted the significant public impact of this severe virus. Zika infections can […]