Category Archives: Infection

CorMedix gains hard-fought approval for combo drug that reduces risk of catheter infection during dialysis

CorMedix went through a lot to secure its FDA approval for DefenCath. There was a reorganization, a CEO change, an exit from Europe, two complete response letters (CRLs) and a switch of manufacturers and suppliers. The green light finally came on Wednesday for the combination treatment which reduces the risk of catheter-related bloodstream infections (CRBSIs) […]

FDA Approves Defencath for Catheter-Related Infections for Those With Kidney Failure

The FDA has approved taurolidine and heparin (Defencath; CorMedix), a catheter lock solution indicated to reduce catheter-related bloodstream infections for adults with kidney failure who are receiving chronic hemodialysis via central venous catheter (CVC), according to a press release from the agency. The approval is limited to this specific patient population.1 Crystal light – stock.adobe.com […]

FDA Approves Liquid Form of Antibiotic for The Treatment of Infection

The FDA has approved metronidazole (Likmez; Kesin Pharma Corporation) oral suspension, 500 mg/5mL, a liquid form of the original antibiotic, for patients that have difficulty swallowing, dysphagia, or high taste sensitivities and struggle to adhere to the original antibiotic, according to a recent press release. The 200 mL bottle features a strawberry peppermint flavored suspension […]

Latest surveillance data shows a rise in antibiotic resistant infections and associated deaths

The latest national surveillance data, announced at the UK Health Security Agency (UKHSA) annual conference in Leeds today, shows that an estimated 58,224 people in England had an antibiotic resistant infection in 2022 – a rise of 4% since 2021 (55,792). Deaths due to severe antibiotic resistant infections also increased from 2021 to 2022 (from […]

Patients at Salem Hospital may have been exposed to hepatitis, HIV

Nearly 450 patients at Salem Hospital may have been exposed to Hepatitis B, Hepatitis C, and HIV due to bad practices when administering IV medications, hospital officials said Wednesday. A spokesperson for the Mass General Brigham system, which owns Salem Hospital, said they were first made aware of the issue earlier this year and said […]

Immune response that protects against infections also drives HIV latency

An immune response that likely evolved to help fight infections appears to be the mechanism that drives human immunodeficiency virus (HIV) into a latent state, lurking in cells only to erupt anew, researchers at Duke Health report. Publishing Nov. 14 in the journal Nature Microbiology, the research team provides new insights into the vexing process […]

Scorpion Bombs, Infectious Donkeys, And Pigs Vs Elephants: 5 Ways Ancient Warfare Got Weird

They say all’s fair in love and war, but when it comes to Black Death Bombs and sending donkeys infected with deadly pathogens hurtling into the enemy, we’re not sure we agree. Long before Oppenheimer became Death, destroyer of worlds, with the atomic bomb, humans were coming up with creative ways to maim and kill […]

Novel C. diff structures are required for infection, offer new therapeutic targets

A C. diff bacterium (green) with iron particles in red, shown in a reconstructed electron tomogram from STEM-EDS. Credit: James McBride/Vanderbilt University Iron storage “spheres” inside the bacterium C. diff—the leading cause of hospital-acquired infections—could offer new targets for antibacterial drugs to combat the pathogen. A team of Vanderbilt researchers discovered that C. diff (Clostridioides […]

Anti-fungals losing ground against fungal infections in hospitals

Somewhere between one third and one half of hospitalized patients who are infected by the fungus Candida die. This number is on the rise due to increasing resistance to commonly used antifungals. However, the picture is complicated because there are various species of Candida and outcomes depend on patients’ underlying conditions. Now, four researchers in […]

Australia ‘losing the war’ against drug-resistant infection, despite drop in use of antibiotics

A national report has found COVID caused one of the biggest drops in antibiotic use in Australia in decades, but fears remain the country is “losing the war” against drug-resistant infection. Key points: A new report has revealed a drop in antibiotic use in Australia But concerns remain about antimicrobial resistance The head of the AMA says […]