AAV-mediated base-editing therapy ameliorates the disease phenotypes in a mouse model of retinitis pigmentosa

Abstract Base editing technology is an ideal solution for treating pathogenic single-nucleotide variations (SNVs). No gene editing therapy has yet been approved for eye diseases, such as retinitis pigmentosa (RP). Here, we show, in the rd10 mouse model, which carries an SNV identified as an RP-causing mutation in human patients, that subretinal delivery of an […]

Study on the spatial decomposition of the infection probability of COVID-19

Abstract In the course of our observations of the transmission of COVID-19 around the world, we perceived substantial concern about imported cases versus cases of local transmission. This study, therefore, tries to isolate cases due to local transmission (also called community spread) from those due to externally introduced COVID-19 infection, which can be key to […]

Global Blood Plasma Market Surges to $56.55 Billion by 2028, Driven by Rising Demand for Plasma-derived Therapies and Growing Geriatric Population

Dublin, Aug. 15, 2023 (GLOBE NEWSWIRE) — The “Global Blood Plasma Market: Analysis By Demand, By Production Capacity, By Type, By Industry, By Application, By Region, Size & Forecast with Impact Analysis of COVID-19 and Forecast up to 2028” report has been added to ResearchAndMarkets.com’s offering. The global blood plasma market in 2022 was valued […]

Impact of data source choice on multimorbidity measurement: a comparison study of 2.3 million individuals in the Welsh National Health Service

Study design and population This cross-sectional study used routinely collected anonymised data available in the SAIL Databank and consisted of individuals of all ages living in Wales and registered with a GP contributing data to the Secure Anonymised Information Linkage (SAIL) Databank on 1 January 2019. Intentionally, this study examines condition coding outside the COVID-19 […]

New outpatient clinic, OSF Cardiovascular Care with Bellin Health hosts blessing

Courtesy photo OSF HealthCare and Bellin Health representatives at the blessing and open house include: front row: Sister Theresa Ann, O.S.F.; Carol Friesen, Eastern Region CEO, OSF HealthCare; Nuno Gomes, Cardiovascular, Pulmonary, and Nephrology Service Line Director, Bellin Health; Kelly Jefferson, President, OSF HealthCare St. Francis Hospital & Medical Group, Dr. Christine Rattin, Cardiologist, Bellin […]

Mosquitoes infected with West Nile Virus found in Sharon, PA

One in five who are infected by WNV will develop mild symptoms of fever, headache, body aches, skin rash, and swollen lymph glands. One in 150 will contract an infection called West Nile encephalitis, which carries symptoms of fever, headache, stiffness in the neck, disorientation, and in some cases coma, tremors, convulsions, and paralysis. 

Dendritic cell vaccines in cancer treatment

Partner contentMedTech Dendritic cell treatment is a type of сancer immunotherapy that uses “lab-trained” immune cells to successfully find and destroy malignant neoplasms throughout the body. It is a prime candidate for adding to the cancer treatment armamentarium, as it significantly improves patient survival when used in combination with conventional treatments. Currently, dendritic cell therapy […]

MDHHS warns residents of legionellosis during common infection season

MICHIGAN (WNEM) – The Michigan Department of Health and Human Services (MDHHS) is reminding residents to be aware of legionellosis, a respiratory infection that is most common in summer and early fall. Legionellosis is a respiratory infection caused by Legionella bacteria, MDHHS said. It can present as Legionnaires’ disease with symptoms of fever, cough, shortness of breath, […]