Cancer and neoplasms

Lymphohematopoietic cancer mortality among Korean semiconductor manufacturing workers

Posted on by yun
02
Aug

Female operators working in the semiconductor industry in South Korea experienced excess cancer mortality due to malignant neoplasms in the lymphoid, hematopoietic, and related tissues, especially leukemia. Female operators showed a 2.59-fold increased risk of mortality due to malignant neoplasms in the lymphoid, hematopoietic, and related tissues compared with the general population and 2.92-fold increased […]

Continue reading →
Blood

Personalised nutrition app uncovers how hormonal cycle impacts blood sugar control

Posted on by yun
02
Aug

Austrian startup Hello Inside was developed to ’empower’ consumers ito reduce their energy spikes and crashes through better blood sugar control knowledge. Launched in May 2022, the app has hit the mark with female consumers who have been made aware of a change in their blood sugar responses throughout the month and have started to […]

Continue reading →
Infection

Co-evolution of immunity and seasonal influenza viruses

Posted on by yun
02
Aug

Abstract Seasonal influenza viruses cause recurring global epidemics by continually evolving to escape host immunity. The viral constraints and host immune responses that limit and drive the evolution of these viruses are increasingly well understood. However, it remains unclear how most of these advances improve the capacity to reduce the impact of seasonal influenza viruses […]

Continue reading →
Congenital disorders

Association between antenatal corticosteroids and risk of serious infection in children: nationwide cohort study

Posted on by yun
02
Aug

Abstract Objective To investigate the associations between exposure to antenatal corticosteroids and serious infection in children during the first three, six, and 12 months of life. Design Nationwide cohort study. Setting National Health Insurance Research Database, Birth Reporting Database, and Maternal and Child Health Database, 1 January 2008 to 31 December 2019, to identify all […]

Continue reading →
Congenital disorders

OPG/RANK/RANKL axis relation to cardiac iron-overload in children with transfusion-dependent thalassemia

Posted on by yun
02
Aug

Abstract OPG/RANK/RANKL axis was reportedly involved in initiating various diseases, especially bone and cardiovascular diseases. This study aimed to assess the relationship between some OPG, RANK, and RANKL polymorphisms and alleles and iron-overload-induced cardiomyopathy in children with transfusion-dependent thalassemia (TDT). This study included 80 TDT children and 80 age and sex-matched controls. Real-time PCR was […]

Continue reading →
Blood

Noninvasive disruption of the blood-brain barrier in the marmoset monkey

Posted on by yun
02
Aug

Abstract The common marmoset monkey (Callithrix jacchus) is a species of rising prominence in the neurosciences due to its small size, ease of handling, fast breeding, and its shared functional and structural brain characteristics with Old World primates. With increasing attention on modeling human brain diseases in marmosets, understanding how to deliver therapeutic or neurotropic […]

Continue reading →
Cancer and neoplasms

Alzheimer’s Disease Market Predicted to Surge at a CAGR of 20% During the Study Period (2019–2032), Assesses DelveInsight

Posted on by yun
02
Aug

New York, USA, Aug. 02, 2023 (GLOBE NEWSWIRE) — Alzheimer’s Disease Market Predicted to Surge at a CAGR of 20% During the Study Period (2019–2032), Assesses DelveInsight The Alzheimer’s disease market size is projected to grow significantly during the forecast period (2023–2032) owing to the launch of upcoming therapies and the increasing prevalence of the […]

Continue reading →
Congenital disorders

Two-sample Mendelian randomization study does not reveal a significant relationship between cytomegalovirus (CMV) infection and autism spectrum disorder

Posted on by yun
02
Aug

ASD affects people worldwide and brings both health and economic burdens. As a widely known virus affecting the CNS in paediatric patients, CMV has long been suggested as a risk factor for ASD, yet no definite evidence has been found. To investigate whether CMV infection has a causal relationship with ASD, we conducted 3 MR […]

Continue reading →
Cancer and neoplasms

MD Anderson Research Highlights for August 2, 2023

Posted on by yun

Newswise — HOUSTON ― The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. Recent developments include a novel biomarker […]

Continue reading →
Cancer and neoplasms

Netrin-1 blockade inhibits tumour growth and EMT features in endometrial cancer

Posted on by yun
02
Aug

Abstract Netrin-1 is upregulated in cancers as a protumoural mechanism1. Here we describe netrin-1 upregulation in a majority of human endometrial carcinomas (ECs) and demonstrate that netrin-1 blockade, using an anti-netrin-1 antibody (NP137), is effective in reduction of tumour progression in an EC mouse model. We next examined the efficacy of NP137, as a first-in-class […]

Continue reading →