What can be done to reduce the risk of heart disease? Cardiovascular disease is the leading cause of death for people ages 65 and older, and as the U.S. population ages, more people will be at-risk of developing heart conditions. Over the next few decades, rates of cardiovascular disease are expected to increase significantly. In […]
Blood
RWJBarnabas Health Continues Urgent Call for Blood and Platelet Donations Throughout The Summer
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Emergency Shortage of Type O Blood and Platelets Heightened During Summer West Orange, NJ, July 26, 2023 – RWJBarnabas Health is continuing to make an urgent appeal for blood and platelet donations as it responds to a serious shortage at hospitals throughout the state. The entire state is currently managing with less than a 3-day […]
Cancer and neoplasms
The relation between obesity and breast cancer risk in women by considering menstruation status and geographical variations: a systematic review and meta-analysis
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Identification and description of the studies One hundred and two studies were included in this meta-analysis. Forty eight studies reported an association between obesity and breast cancer in pre-menopausal women, and 67 studies showed a relationship between obesity and breast cancer in post-menopausal women. 34 studies (4 cross-sectional,18 case–control, and 12 cohort) with a total […]
Khan MAB, Hashim MJ, King JK, Govender RD, Mustafa H, Al Kaabi J. Epidemiology of type 2 diabetes–global burden of disease and forecasted trends. J Epidemiol Global Health. 2020;10(1):107. Article Google Scholar Zinman B, Wanner C, Lachin JM, Fitchett D, Bluhmki E, Hantel S, Mattheus M, Devins T, Johansen OE, Woerle HJ, et al. Empagliflozin, […]
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Abstract Recent studies have documented frequent evolution of clones carrying common cancer mutations in apparently normal tissues, which are implicated in cancer development1,2,3. However, our knowledge is still missing with regard to what additional driver events take place in what order, before one or more of these clones in normal tissues ultimately evolve to cancer. […]
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The Cornell University Hospital for Animals has added a cutting-edge service for companion animals: a new technology capable of cleansing patients’ blood outside of their bodies. This opens the door to several new treatment options, including dialysis for animals with kidney failure and immune-mediated diseases. The new technology – an extracorporeal blood purification (EBP) unit […]
Infection
Multiple refractory intracellular pathogen infections in a human immunodeficiency virus-negative patient with anti-interferon-γ autoantibodies: a case report
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Döffinger R, Helbert MR, Barcenas-Morales G, Yang K, Dupuis S, Ceron-Gutierrez L, Espitia-Pinzon C, Barnes N, Bothamley G, Casanova JL, Longhurst HJ, Kumararatne DS. Autoantibodies to interferon-gamma in a patient with selective susceptibility to mycobacterial infection and organ-specific autoimmunity. Clin Infect Dis. 2004;38(1):e10–4. Article PubMed Google Scholar Browne SK, Burbelo PD, Chetchotisakd P, Suputtamongkol Y, […]
Cancer and neoplasms
Clinical outcome of Mantle Cell Lymphoma patients with high-risk disease (high-risk MIPI-c or high p53 expression)
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Abstract Currently, treatment allocation of patients with Mantle Cell Lymphoma (MCL) is mainly based on age and medical fitness. The combined MCL International Prognostic Index (MIPI-c) allows to predict prognosis using clinical factors (MIPI) and the Ki-67 index. However, high p53 expression as surrogate for TP53 alterations has demonstrated to be an independent predictor for […]
Congenital disorders
Association between Autism Spectrum Disorder (ASD) and vision problems. A systematic review and meta-analysis
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Abstract Aim To conduct a systematic review and meta-analysis assessing whether vision and/or eye disorders are associated with Autism Spectrum Disorder (ASD). Method Based on a pre-registered protocol (PROSPERO: CRD42022328485), we searched PubMed, Web of Knowledge/Science, Ovid Medline, Embase and APA PsycINFO up to 5th February 2022, with no language/type of document restrictions. We included […]
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SARANAC LAKE — Following a season of declining donations, the American Red Cross has put out a call for help as it seeks to avert a shortage of blood. When a donor makes and keeps an appointment to give blood or platelets in the weeks ahead, they can help ensure trauma patients, those undergoing cancer […]