Cardiovascular

Vitamin D Supplementation and Major Cardiovascular Events: D-Health Randomised Controlled Trial

Posted on by yun
28
Jun

Abstract Objective To investigate whether supplementing older adults with monthly doses of vitamin D alters the incidence of major cardiovascular events. Design Randomised, double blind, placebo controlled trial of monthly vitamin D (the D-Health Trial). Computer generated permuted block randomisation was used to allocate treatments. Setting Australia from 2014 to 2020. Participants 21 315 participants aged […]

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Congenital disorders

Mothers aged 23 to 32 ‘least likely to have babies with congenital disorders’

Posted on by yun
27
Jun

Mothers aged between 23 and 32 are less likely to have babies with congenital disorders than older and younger women, research suggests. Women who have a baby before the age of 23 face a 20 per cent higher chance of it developing abnormalities, data show, while those over the age of 32 are 15 per […]

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Congenital disorders

New Model Provides Unprecedented Window Into Human Embryonic Development

Posted on by yun
27
Jun

Two to three weeks after conception, an embryo faces a critical point in its development. In the stage known as gastrulation, the transformation of embryonic cells into specialized cells begins. This initiates an explosion of cellular diversity in which the embryonic cells later become the precursors of future blood, tissue, muscle, and more types of […]

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Cancer and neoplasms

Antibody drug conjugates: A shift in treatment options for solid tumors

Posted on by yun
23
Jun

Antibody drug conjugates have existed for years, but several recent advances are helping to refine how these cancer drugs work, expanding our understanding to help overcome their challenges and, ultimately, extending their benefit to more patients. “Antibody drug conjugates are an exciting field of drug development,” says Funda Meric-Bernstam, M.D., chair of Investigational Cancer Therapeutics. […]

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Cardiovascular

Beating cardiovascular disease — the role of Europe’s environment

Posted on by yun
22
Jun

Understanding the issue Cardiovascular disease (CVD) impacts the lives of many European residents. It is the most common cause of death in EEA member countries. Every year in the EU, more than 6 million new cases of CVD are diagnosed and over 1.7 million people die from diseases of the circulatory system, representing around 37% […]

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Cardiovascular

Health Bosses Warn of Heart Disease Emergency in England

Posted on by yun
21
Jun

England is engulfed in a cardiovascular disease emergency, health bosses have said, as stark figures reveal there have been almost 100,000 excess deaths since the start of the Covid pandemic. Analysis of official government data suggests that more than 500 people a week are dying needlessly from heart disease, heart attacks or strokes. There have […]

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Congenital disorders

Use of Ambroxol as Therapy for Gaucher Disease

Posted on by yun

Key Points Question  What are the biochemical changes associated with ambroxol repurposing among patients with Gaucher disease who have not received any disease-specific treatment? Findings  In this case series of 28 unselected participants, significant improvements in hematologic parameters, visceral volumes, and plasma biomarkers were observed for 26 patients after a mean (SD) treatment duration of […]

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Cardiovascular

Study Reveals That Wine Consumption Has an Inverse Relationship to Cardiovascular Mortality

Posted on by yun
20
Jun

In a recent study published in the Nutrients Journal, researchers aimed to understand the association between wine consumption and cardiovascular mortality, cardiovascular disease (CVD), and coronary heart disease (CHD). The researchers performed a systematic review and meta-analysis using longitudinal studies, including cohort and case-control studies retrieved from multiple databases, which they searched from their inception […]

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