Serious Infections were Rare Among Patients with PsA, axSpA

Although nonserious infections were common, serious infections were rare in both randomized controlled trials (RCTs) and real-life studies of patients with psoriatic arthritis (PsA) or axial spondyloarthritis (axSpA), according to a study published in Rheumatic and Musculoskeletal Diseases.1 Fabienne Coury, MD, PhD Credit: ResearchGate “Most of the data on the risk of infection in patients treated […]

Dr Zhou on the Evaluation of Combination Therapies With Ruxolitinib in Myelofibrosis

Amy W. Zhou, MD, assistant professor, Department of Medicine, Division of Hematology, Washington University School of Medicine in St. Louis, discusses the investigation of ruxolitinib (Jakafi) given in conjunction with novel or emerging agents such as pacritinib (Vonjo) and momelotinib (Ojjaara), highlighting these agents’ potential at contributing to the treatment paradigm in myelofibrosis. Combination therapies involving […]

Walking more than five flights of stairs a day can cut risk of heart disease by 20%, study says

<div data-thumb="https://scx1.b-cdn.net/csz/news/tmb/2023/walking-more-than-five.jpg" data-src="https://scx2.b-cdn.net/gfx/news/hires/2023/walking-more-than-five.jpg" data-sub-html="Credit: Atherosclerosis (2023). DOI: 10.1016/j.atherosclerosis.2023.117300″> Credit: Atherosclerosis (2023). DOI: 10.1016/j.atherosclerosis.2023.117300 Forget walking 10,000 steps a day. Taking at least 50 steps climbing stairs each day could significantly slash your risk of heart disease, according to a new study from Tulane University. The study, published in Atherosclerosis, found that climbing more than five […]

Public warned as cryptosporidiosis outbreak hits regional Queensland city

Queensland Health is investigating a highly infectious disease outbreak in Gladstone caused by microscopic parasites. Key points: The Central Queensland Hospital and Health Service confirmed the outbreak of cryptosporidiosis, reporting 12 cases in recent weeks and 31 so far this year. The region typically sees 32 cases per year. Queensland Health data shows, statewide, there have been […]

Capturing the Nuances of Immune Cells Using Glycobiology

In the continued quest for truly personalized medicine, biomarker discovery has expanded far beyond genomics and proteomics. Scientists are increasingly interested in glycans, the carbohydrates that link to proteins and lipids in a process known as glycosylation. Glycosylation is a fundamental regulator of countless biological activities, including immune cell function in health and disease. Research […]

High Blood Pressure in Adolescence Increases Cardiovascular Event Risk, Study Finds

Credit: CDC/Unsplash Elevated blood pressure in late adolescence was associated with a substantial and gradual absolute risk for major cardiovascular events in adulthood, beginning at a blood pressure level of 120/80 mmHg, according to new research.1 With up to 50 years of follow-up in a cohort of more than 1 million men, the analysis suggests […]