Pictured: Illustration of a blood clot in a blood vessel/iStock, libre de droit Anthos Therapeutics is ending the Phase II AZALEA-TIMI 71 study ahead of schedule after its investigational monoclonal antibody abelacimab demonstrated an “overwhelming reduction” in bleeding compared to Bayer and Johnson & Johnson’s Xarelto (rivaroxaban), the company announced Monday. Patients treated with abelacimab saw […]
September 18, 2023 2 min read Source/Disclosures Published by: Disclosures: Lachenal reports no relevant financial disclosures. Please see the study for all other authors’ relevant financial disclosures. ADD TOPIC TO EMAIL ALERTS Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted […]
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Abstract Recurrent and severe infections occurred in children with Down Syndrome (DS) due to immunological parameter defects have been reported. The aim of the study is to evaluate the importance of using T-cell receptor excision circle (TREC) and kappa-deleting recombination excision circle (KREC) as molecular markers for immunological investigation of children with DS. The study […]
Myelofibrosis is an uncommon form of blood cancer that can cause an enlarged spleen; constitutional symptoms such as night sweats, fever and weight loss; and scarring in the bone marrow. The bone marrow scarring also leads to severe anemia, which can cause fatigue and weakness. Blood transplants and bone marrow transplants are among the few […]
September 18, 2023 People with atrial fibrillation (AFib) are at risk for bleeding while taking direct oral anticoagulants, but a groundbreaking new option is on the horizon. Anthos Therapeutics announced today that AZALEA-TIMI 71 Phase 2 study in 1,287 patients with atrial fibrillation has been stopped early after meeting its primary endpoint. The study results […]
The link between migraine and cardiovascular disease is complex and involves overlapping mechanisms, such as endovascular disturbances. Challenges in measuring migraine, in distinguishing between causation and prediction, and in the understanding of clinical implications highlight the need for further research to guide treatment and cardiovascular risk assessment for the millions of individuals living with migraine. […]
Houston, TX, Sept. 18, 2023 (GLOBE NEWSWIRE) — Zion Market Research has published a new research report titled “Newborn Screening Instruments Market By Test Type (Blood Spot Test, Hearing Test, Critical Congenital Heart Disease (CCHD) Test, And Metabolic Disorder Test), By Product Type (Mass Spectrometers, Pulse Oximeters, Hearing Screening Devices, Assay Kits, And DNA Sequencers), […]
Washington, DC, Sept. 18, 2023 (GLOBE NEWSWIRE) — Zion Market Research has published a new research report titled “Medical Inhaled Nitric Oxide Market By Product Type (Inhaled Nitric Oxide Delivery Systems, Nitric Oxide Sensors, And Monitors), By Route Of Administration (Inhaled Nitric Oxide Gas And Inhaled Nitric Oxide With Oxygen Mixtures), By Application (Cardiovascular Disorders […]
Abstract Ae. aegypti mosquitoes transmit some of the most important human viral diseases that are responsible for a significant public health burden worldwide. The small interfering RNA (siRNA) pathway is considered the major antiviral defense system in insects. Here we show that siRNA pathway disruption by CRISPR/Cas9-based Ago2 knockout impaired the mosquitoes’ ability to degrade […]